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Machine translation
1. (WO2010122504) THIAZOLE DERIVATIVES AND THEIR USE AS P2Y12 RECEPTOR ANTAGONISTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/122504    International Application No.:    PCT/IB2010/051742
Publication Date: 28.10.2010 International Filing Date: 21.04.2010
IPC:
C07D 417/04 (2006.01), C07F 9/38 (2006.01), A61K 31/496 (2006.01), A61P 7/02 (2006.01), A61P 9/10 (2006.01)
Applicants: ACTELION PHARMACEUTICALS LTD [CH/CH]; Gewerbestrasse 16 CH-4123 Allschwil (CH) (For All Designated States Except US).
CAROFF, Eva [FR/FR]; (CH) (For US Only).
HILPERT, Kurt [CH/CH]; (CH) (For US Only).
HUBLER, Francis [FR/CH]; (CH) (For US Only).
LEHMANN, David [CH/CH]; (CH) (For US Only).
MEYER, Emmanuel [CH/CH]; (CH) (For US Only).
RENNEBERG, Dorte [DE/CH]; (CH) (For US Only)
Inventors: CAROFF, Eva; (CH).
HILPERT, Kurt; (CH).
HUBLER, Francis; (CH).
LEHMANN, David; (CH).
MEYER, Emmanuel; (CH).
RENNEBERG, Dorte; (CH)
Agent: GSCHWEND, Thomas; c/o Actelion Pharmaceuticals Ltd. Legal Department Gewerbestrasse 16 CH-4123 Allschwil (CH)
Priority Data:
PCT/IB2009/051647 22.04.2009 IB
Title (EN) THIAZOLE DERIVATIVES AND THEIR USE AS P2Y12 RECEPTOR ANTAGONISTS
(FR) DÉRIVÉS DE THIAZOLE ET LEUR UTILISATION COMME ANTAGONISTES DES RÉCEPTEURS P2Y12
Abstract: front page image
(EN)The present invention relates to thiazole derivatives of Formula (I) and their use as P2Y12 receptor antagonists in the treatment and/or prevention of peripheral vascular, of visceral-, hepatic- and renal-vascular, of cardiovascular and of cerebrovascular diseases or conditions associated with platelet aggregation, including thrombosis in humans and other mammals.
(FR)La présente invention concerne des dérivés de thiazole de formule (I) et leur utilisation comme antagonistes des récepteurs P2Y12 dans le traitement et/ou la prévention de maladies ou pathologies vasculaires périphériques, viscérovasculaires, hépatovasculaires et rénovasculaires, cardiovasculaires et cérébrovasculaires associées à une agrégation plaquettaire, notamment la thrombose chez les humains et autres mammifères.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)