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1. (WO2010122452) A MEDICINAL ANTIFUNGAL AND STEROID CREAM INCORPORATING A BIOPOLYMER AND A PROCESS TO MAKE IT

Pub. No.:    WO/2010/122452    International Application No.:    PCT/IB2010/051609
Publication Date: Fri Oct 29 01:59:59 CEST 2010 International Filing Date: Thu Apr 15 01:59:59 CEST 2010
IPC: A61K 9/06
A61K 8/06
A61K 8/73
A61K 47/36
A61Q 19/00
A61K 31/57
A61K 31/415
A61P 17/02
Applicants: VANANGAMUDI, Sulur, Subramaniam
SRINIVASAN, Madhavan
CHULLIEL, Neelakandan Narayanan
SELVARAJ, Balkrishnana
Inventors: VANANGAMUDI, Sulur, Subramaniam
SRINIVASAN, Madhavan
CHULLIEL, Neelakandan Narayanan
SELVARAJ, Balkrishnana
Title: A MEDICINAL ANTIFUNGAL AND STEROID CREAM INCORPORATING A BIOPOLYMER AND A PROCESS TO MAKE IT
Abstract:
The present invention is directed to a composition for treating fungal skin infections & skin inflammation, along with skin rejuvenation. More particularly, the present invention relates to a pharmaceutical cream comprising a biopolymer, a corticosteroid and an antifungal active ingredient. It discloses a composition for treating fungal skin infections & skin inflammation, along with skin rejuvenation containing a) a biopolymer in the form of chitosan, b) a combination of active pharmaceutical ingredients (APIs), clotrimazole and hydrocortisone acetate used in treating fungal skin infections & skin inflammations, c) a cream base containing primary and secondary emulsifiers, waxy materials, co-solvents, acids, preservatives, buffering agents, anti oxidants, chelating agents, and humectants and d) water. The active ingredients, namely chitosan, corticosteroid in the form of hydrocortisone acetate, and an antifungal agent in the form of clotrimazole, are incorporated in cream base for use in treating fungal skin infections and skin inflammation due to allergy & itching, & wounds on human skin involving contacting human skin with the above identified composition.