Search International and National Patent Collections

1. (WO2010122090) FGFR1C ANTIBODY COMBINATIONS

Pub. No.:    WO/2010/122090    International Application No.:    PCT/EP2010/055320
Publication Date: Fri Oct 29 01:59:59 CEST 2010 International Filing Date: Fri Apr 23 01:59:59 CEST 2010
IPC: A61P 3/04
A61K 39/395
C07K 14/605
C07K 16/28
C07K 19/00
Applicants: GLAXO GROUP LIMITED
BEATON, Andrew
CLEVELAND, Sean, Matthew
GOUGH, Gerald, Wayne
PAULIK, Mark, Andrew
Inventors: BEATON, Andrew
CLEVELAND, Sean, Matthew
GOUGH, Gerald, Wayne
PAULIK, Mark, Andrew
Title: FGFR1C ANTIBODY COMBINATIONS
Abstract:
The invention relates to combinations of FGFR1c antagonists with agonist peptides and provides dual targeting proteins which bind to FGFR1c comprising an antigen binding protein which is capable of binding to FGFR1c and which is linked to one or more agonist peptides, methods of making such constructs and uses thereof, particularly in treating obesity.