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1. (WO2010122064) SUBSTITUTED NAPHTHYRIDINE DERIVATIVES AND THEIR MEDICAL USE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2010/122064 International Application No.: PCT/EP2010/055284
Publication Date: 28.10.2010 International Filing Date: 21.04.2010
IPC:
C07D 471/04 (2006.01) ,A61K 31/4375 (2006.01) ,A61P 25/00 (2006.01)
Applicants: BROWN, William, Dalby[DK/DK]; DK (UsOnly)
JESSEN, Carsten[DK/DK]; DK (UsOnly)
MATTSSON, Cecilia[SE/SE]; SE (UsOnly)
SOTT, Richard[SE/SE]; SE (UsOnly)
STRØBÆK, Dorte[DK/DK]; DK (UsOnly)
NEUROSEARCH A/S[DK/DK]; Pederstrupvej 93 DK-2750 Ballerup, DK (AllExceptUS)
Inventors: BROWN, William, Dalby; DK
JESSEN, Carsten; DK
MATTSSON, Cecilia; SE
SOTT, Richard; SE
STRØBÆK, Dorte; DK
Common
Representative:
NEUROSEARCH A/S; Patent Department Pederstrupvej 93 DK-2750 Ballerup, DK
Priority Data:
61/172,82227.04.2009US
PA 2009 0051621.04.2009DK
Title (EN) SUBSTITUTED NAPHTHYRIDINE DERIVATIVES AND THEIR MEDICAL USE
(FR) DÉRIVÉS DE NAPHTYRIDINE SUBSTITUÉS ET LEUR UTILISATION MÉDICALE
Abstract: front page image
(EN) The present application discloses novel substituted naphthyridine derivatives of Formula (I) and their use as modulators of the voltage gated Kv7 (KCNQ) potassium ion channels.In other aspects the application discloses the use of these compounds, in a method for therapy and to pharmaceutical compositions comprising these compounds.
(FR) La présente invention porte sur de nouveaux dérivés de naphtyridine substitués de formule (I) et sur leur utilisation comme modulateurs des canaux potassiques dépendant d'un potentiel d'action Kv7 (KCNQ). Dans d'autres aspects l'invention porte sur l'utilisation de ces composés, dans un procédé de thérapie et sur des compositions pharmaceutiques comprenant ces composés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)