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1. (WO2010121904) PROCESS FOR THE IODINATION OF AROMATIC COMPOUNDS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2010/121904 International Application No.: PCT/EP2010/054624
Publication Date: 28.10.2010 International Filing Date: 08.04.2010
IPC:
C07C 227/16 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
227
Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
14
from compounds containing already amino and carboxyl groups or derivatives thereof
16
by reactions not involving the amino or carboxyl groups
Applicants: CITTERIO, Attilio[IT/IT]; IT (UsOnly)
LATTUADA, Luciano[IT/IT]; IT (UsOnly)
FERRIGATO, Aurelia[IT/IT]; IT (UsOnly)
FRETTA, Roberta[IT/IT]; IT (UsOnly)
MAZZON, Roberta[IT/IT]; IT (UsOnly)
MELI, Gabriele[IT/IT]; IT (UsOnly)
LEONARDI, Gabriella[IT/IT]; IT (UsOnly)
UGGERI, Fulvio[IT/IT]; IT (UsOnly)
VIGNALE, Evelin[IT/IT]; IT (UsOnly)
VISIGALLI, Massimo[IT/IT]; IT (UsOnly)
BRACCO IMAGING SPA[IT/IT]; Via Egidio Folli, 50 I-20134 Milano, IT (AllExceptUS)
Inventors: CITTERIO, Attilio; IT
LATTUADA, Luciano; IT
FERRIGATO, Aurelia; IT
FRETTA, Roberta; IT
MAZZON, Roberta; IT
MELI, Gabriele; IT
LEONARDI, Gabriella; IT
UGGERI, Fulvio; IT
VIGNALE, Evelin; IT
VISIGALLI, Massimo; IT
Agent: Merli, Silvia; Bracco Imaging SpA Via XXV Aprile No. 4 I-20097 San Donato Milanese, IT
Priority Data:
09158319.521.04.2009EP
Title (EN) PROCESS FOR THE IODINATION OF AROMATIC COMPOUNDS
(FR) PROCÉDÉ POUR L'IODATION DE COMPOSÉS AROMATIQUES
Abstract:
(EN) The present invention relates to a process for the preparation of iodinated anilines; in particular, it relates to a process including the direct iodination, with suitably activated iodine, of 3,5-disubstituted anilines to the corresponding 3,5- disubstituted-2,4,6-triiodoanilines, which are useful intermediates for the synthesis of x-ray contrast media, and to the preparation of the contrast media themselves.
(FR) La présente invention porte sur un procédé pour la préparation d'anilines iodées ; en particulier, elle porte sur un procédé comprenant l'iodation directe, avec de l'iode activé de façon appropriée, d'anilines 3,5-disubstituées en les 2,4,6-triiodoanilines 3,5-disubstituées correspondantes, qui sont des intermédiaires utiles pour la synthèse de produits de contraste pour les rayons X, et sur la préparation des produits de contraste eux-mêmes.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)