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1. (WO2010121455) A DRUG COMPOSITION FOR TREATING TUMOR WITH POLYMERIC MICELLE ENCAPSULATING ANTINEOPLASTIC

Pub. No.:    WO/2010/121455    International Application No.:    PCT/CN2009/073382
Publication Date: Fri Oct 29 01:59:59 CEST 2010 International Filing Date: Fri Aug 21 01:59:59 CEST 2009
IPC: A61K 47/30
C08G 63/91
A61K 9/00
A61P 35/00
Applicants: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
财团法人工业技术研究院
HSU, Yuan-Hung
许源宏
HSUEH, Chu Chun
薛竹君
CNANG, Yuan-Chia
张原嘉
LU, Jui-Mei
吕瑞梅
KAN, Pei
甘霈
Inventors: HSU, Yuan-Hung
许源宏
HSUEH, Chu Chun
薛竹君
CNANG, Yuan-Chia
张原嘉
LU, Jui-Mei
吕瑞梅
KAN, Pei
甘霈
Title: A DRUG COMPOSITION FOR TREATING TUMOR WITH POLYMERIC MICELLE ENCAPSULATING ANTINEOPLASTIC
Abstract:
A drug composition for treating tumor and a method for improving the solubility and the blood circulating time of antineoplastics as well as a method for delivering the drug to one type or more types of solid tumors are disclosed. The composition comprises at least one polymeric micelle and at least one antineoplastic agent encapsulated in the micelle. The polymeric micelle comprises a block copolymer, wherein the block copolymer comprises at least one hydrophilic polymer, at least one hydrophobic polymer, and at least one zwitterion. The method comprises administration of the drug composition.