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1. (WO2010121361) TISSUE KALLIKREIN FOR THE TREATMENT OF HUNTINGTON'S DISEASE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2010/121361 International Application No.: PCT/CA2010/000575
Publication Date: 28.10.2010 International Filing Date: 22.04.2010
IPC:
A61K 38/48 (2006.01) ,A61P 25/28 (2006.01)
Applicants: WILLIAMS, Mark[CA/CA]; CA (UsOnly)
CHARLES, Matthew[CA/CA]; CA (UsOnly)
SANOMUNE INC.[CA/CA]; 7 - 1250 Waverley Street Winnipeg, Manitoba R3T 6C6, CA (AllExceptUS)
Inventors: WILLIAMS, Mark; CA
CHARLES, Matthew; CA
Agent: RIDOUT & MAYBEE LLP; 225 King Street West 10 th Floor Toronto, Ontario M5V 3M2, CA
Priority Data:
61/171,57922.04.2009US
Title (EN) TISSUE KALLIKREIN FOR THE TREATMENT OF HUNTINGTON'S DISEASE
(FR) KALLICRÉINE TISSULAIRE POUR LE TRAITEMENT DE LA MALADIE D'HUNTINGTON
Abstract:
(EN) This invention relates to methods of treating the prodrome and adult onset stage of Huntington's disease or symptoms thereof, and or Juvenile Huntington's disease symptoms thereof. Methods of the invention include administering a therapeutically effective amount of tissue kallikrein, variants or active fragments thereof. The invention further relates to pharmaceutical compositions comprising a therapeutically effective amount of tissue kallikrein, variants or active fragments thereof formulated for oral or intranasal administration.
(FR) Cette invention porte sur des procédés de traitement du stade de prodrome et d'initiation adulte de la maladie de Huntington ou de symptômes de celle-ci, et/ou de la maladie de Huntington juvénile ou de symptômes de celle-ci. Les procédés de l'invention comprennent l'administration d'une quantité thérapeutique efficace de kallicréine tissulaire, de variants ou de fragments actifs de celle-ci. L'invention porte en outre sur des compositions pharmaceutiques comportant une quantité thérapeutique efficace de kallicréine tissulaire, de variants ou de fragments actifs de celle-ci formulés pour une administration orale ou intra-nasale.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)