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1. (WO2010121163) FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/121163    International Application No.:    PCT/US2010/031434
Publication Date: 21.10.2010 International Filing Date: 16.04.2010
IPC:
C09B 23/01 (2006.01), C09B 23/08 (2006.01), G01N 33/58 (2006.01), C09B 23/00 (2006.01)
Applicants: LI-COR, INC. [US/US]; 4647 Superior Street Lincoln, Nebraska 68504 (US) (For All Designated States Except US).
XU, Xinshe [CA/US]; (US) (For US Only).
DRANEY, Daniel R. [US/US]; (US) (For US Only)
Inventors: XU, Xinshe; (US).
DRANEY, Daniel R.; (US)
Agent: SNYDER, Joseph R.; Townsend and Townsend and Crew LLP Two Embarcadero Center, Eighth Floor San Francisco, California 94111-3834 (US)
Priority Data:
61/170,579 17.04.2009 US
61/184,750 05.06.2009 US
Title (EN) FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES
(FR) IMAGERIE DE FLUORESCENCE AVEC DES COLORANTS DE CYANINE SUBSTITUÉE
Abstract: front page image
(EN)Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared spectral range. The cyanine compounds of Formula (I) are presented: (I). wherein Q is a portion of a polymethine bridge selected from the group consisting of: (a) and (b). Also included are bioconjugates of the compounds of Formula (I), methods of labeling biomolecules with the compounds, and methods of imaging.
(FR)La présente invention concerne des composés et des procédés qui sont utiles pour l'imagerie non invasive dans la gamme spectrale de l'infrarouge proche. Les composés de cyanine de formule (I) sont présentés : (I) dans laquelle Q est une partie d'un pont polyméthine choisie dans le groupe constitué de : (a) et (b). La présente invention concerne en outre des bioconjugués des composés de formule (I), des procédés de marquage de biomolécules avec les composés, et des procédés d'imagerie.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)