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1. (WO2010121101) SURFACE MODIFICATION FOR ENHANCED SILANATION OF CERAMIC MATERIALS

Pub. No.:    WO/2010/121101    International Application No.:    PCT/US2010/031348
Publication Date: Fri Oct 22 01:59:59 CEST 2010 International Filing Date: Sat Apr 17 01:59:59 CEST 2010
IPC: A61K 6/00
A61L 27/30
Applicants: RESEARCH TRIANGLE INSTITUTE
NOVA SOUTHEASTERN UNIVERSITY
PIASCIK, Jeffrey Robert
THOMPSON, Jeffrey Yates
GREGO, Sonia
STONER, Brian R.
Inventors: PIASCIK, Jeffrey Robert
THOMPSON, Jeffrey Yates
GREGO, Sonia
STONER, Brian R.
Title: SURFACE MODIFICATION FOR ENHANCED SILANATION OF CERAMIC MATERIALS
Abstract:
A coated medical implant, such as a coated dental component, is provided, the coated medical implant including a substrate surface formed of a material comprising available hydroxyl groups and a silicon oxide coating layer chemisorbed on the substrate surface. A method for the preparation of such coated implants is also provided, the method involving application of the silicon oxide coating layer to the substrate surface by chemical vapor deposition. A dental structure is also provided, which includes a first dental component having a substrate surface formed of a material comprising available hydroxyl groups; a silicon oxide coating layer chemisorbed on the substrate surface; a silane coupling agent overlying and covalently attached to the silicon oxide layer; a dental cement overlying and coupled to the silane coupling agent; and a second dental component having a surface bonded to the dental cement.