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Machine translation
1. (WO2010121051) BIOCOMPATIBLE PHASE INVERTIBLE PROTEINACEOUS COMPOSITIONS AND METHODS FOR MAKING AND USING THE SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/121051    International Application No.:    PCT/US2010/031272
Publication Date: 21.10.2010 International Filing Date: 15.04.2010
IPC:
C08G 63/91 (2006.01), C08L 67/00 (2006.01)
Applicants: TENAXIS MEDICAL, INC. [US/US]; 835 Maude Avenue Mountain View, California 94043 (US) (For All Designated States Except US).
HANDLEY, Ian [US/US]; (US) (For US Only).
WONG, Joanna [US/US]; (US) (For US Only)
Inventors: HANDLEY, Ian; (US).
WONG, Joanna; (US)
Agent: HESLIN, James, M.; Townsend And Townsend And Crew LLP Two Embarcadero Center 8th Floor San Francisco, California 94111-3834 (US)
Priority Data:
61/170,545 17.04.2009 US
Title (EN) BIOCOMPATIBLE PHASE INVERTIBLE PROTEINACEOUS COMPOSITIONS AND METHODS FOR MAKING AND USING THE SAME
(FR) COMPOSITIONS PROTÉIQUES A PHASES BIOCOMPATIBLES POUVANT ÊTRE INVERSÉES ET LEURS PROCÉDÉS DE FABRICATION ET D'UTILISATION
Abstract: front page image
(EN)Biocompatible phase invertible proteinaceous compositions and methods for making and using the same are provided. The subject phase invertible compositions are prepared by combining a crosslinker and a proteinaceous substrate. The proteinaceous substrate includes one or more proteins and a polyamine, where the polyamine and a proteinaceous substrate are present in synergistic viscosity enhancing amounts, and may also include one or more of: a carbohydrate, a tackifying agent, a plasticizer, or other modification agent. In certain embodiments, the crosslinker is a heat-treated dialdehyde, e.g., heat-treated glutaraldehyde. Also provided are kits for use in preparing the subject compositions. The subject compositions, kits and systems find use in a variety of different applications.
(FR)L'invention concerne des compositions protéiques à phases biocompatibles pouvant être inversées et leurs procédés de fabrication et d'utilisation. Ces compositions à phases pouvant être inversées sont préparées par combinaison d'un réticulant et d'un substrat protéique. Ce dernier comporte au moins une protéine et une polyamine, la polyamine et le substrat protéique sont présents dans des proportions qui renforcent la viscosité synergique, et peuvent également comporter un ou plusieurs: hydrate de carbone, agent collant, plastifiant, ou autre agent de modification. Dans certains modes de réalisation, le réticulant est un dialdéhyde traité thermiquement, par exemple un glutaraldéhyde traité thermiquement. L'invention concerne également des trousses utilisées lors de la préparation desdites compositions. Ces compositions, trousses et systèmes peuvent servir dans diverses applications différentes.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)