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1. (WO2010120621) HEPATITIS C VIRUS INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2010/120621 International Application No.: PCT/US2010/030366
Publication Date: 21.10.2010 International Filing Date: 08.04.2010
IPC:
C07D 513/04 (2006.01) ,A61K 31/428 (2006.01) ,A61P 31/14 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
513
Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/, C07D477/232
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
425
Thiazoles
428
condensed with carbocyclic rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12
Antivirals
14
for RNA viruses
Applicants: LAVOIE, Rico[CA/CA]; CA (UsOnly)
BENDER, John A.[US/US]; US (UsOnly)
BACHAND, Carol[CA/CA]; CA (UsOnly)
RUEDIGER, Edward H.[CA/CA]; CA (UsOnly)
KADOW, John F.[US/US]; US (UsOnly)
BRISTOL-MYERS SQUIBB COMPANY[US/US]; Route 206 and Province Line Road Princeton, New Jersey 08543-4000, US (AllExceptUS)
Inventors: LAVOIE, Rico; CA
BENDER, John A.; US
BACHAND, Carol; CA
RUEDIGER, Edward H.; CA
KADOW, John F.; US
Agent: MINGO, Pamela A.; Bristol-Myers Squibb Company P.O. Box 4000 Princeton, New Jersey 08543-4000, US
Priority Data:
61/168,89113.04.2009US
Title (EN) HEPATITIS C VIRUS INHIBITORS
(FR) INHIBITEURS DU VIRUS DE L'HÉPATITE C
Abstract:
(EN) This disclosure concerns novel compounds of Formula (I) or Formula (II) as defined in the specification and compositions comprising such novel compounds. These compounds are useful antiviral agents, especially in inhibiting the function of the NS5A protein encoded by Hepatitis C virus (HCV). Thus, the disclosure also concerns a method of treating HCV related diseases or conditions by use of these novel compounds or a composition comprising such novel compounds.
(FR) Cette invention porte sur de nouveaux composés de formule (I) ou formule (II) tels que définis dans la description et sur des compositions comprenant de tels nouveaux composés. Ces composés sont des agents antiviraux utiles, notamment dans l'inhibition de la fonction de la protéine NS5A codée par le virus de l'hépatite C (VHC). Ainsi, l'invention concerne également un procédé de traitement de maladies ou d'états liés au VHC par l'utilisation de ces nouveaux composés ou une composition comprenant de tels nouveaux composés.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)