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1. (WO2010120195) MACROCYCLIC LACTONE COMBINATION COMPOSITIONS, VACCINES AND METHODS FOR PRODUCING SAME

Pub. No.:    WO/2010/120195    International Application No.:    PCT/NZ2010/000067
Publication Date: Fri Oct 22 01:59:59 CEST 2010 International Filing Date: Thu Apr 15 01:59:59 CEST 2010
IPC: A61K 39/215
A61K 31/335
A61K 31/365
A61K 39/15
A61P 31/00
Applicants: MERIAL LTD
HOLMES, Robert William Lachlan
RAZZAK, Majid Hameed Abdul
Inventors: HOLMES, Robert William Lachlan
RAZZAK, Majid Hameed Abdul
Title: MACROCYCLIC LACTONE COMBINATION COMPOSITIONS, VACCINES AND METHODS FOR PRODUCING SAME
Abstract:
An injectable composition, capable of preventing or controlling parasitic, viral, or bacterial infections or diseases, for example scours, in pregnant cows and viral infections or diseases in neonatal calves by parenterally administering to each cow in a herd of pregnant cows, a dose of a combination composition comprising: (a) at least one inactivated viral component derived from rotavirus and/or coronavirus; (b) a macrocyclic lactone active compound; and (c) a pharmaceutically acceptable parenteral carrier and preservative. The injectable compositions which include eprinomectin result in extremely low milk residues.