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1. (WO2010120003) TOOTHPASTE COMPOSITION FOR HYPERSENSITIVE-TEETH CONTAINING NANO-SIZED CARBONATE APATITE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/120003    International Application No.:    PCT/KR2009/001956
Publication Date: 21.10.2010 International Filing Date: 16.04.2009
IPC:
A61K 8/19 (2006.01), A61Q 11/00 (2006.01), A61K 8/25 (2006.01)
Applicants: SNU R&DB FOUNDATION [KR/KR]; San 56-1, Sillim-dong, Gwanak-gu Seoul 151-010 (KR) (For All Designated States Except US).
HONG, Kug Sun [KR/KR]; (KR) (For US Only).
JUNG, Hyun Suk [KR/KR]; (KR) (For US Only).
RYU, Hyun Seung [KR/KR]; (KR) (For US Only).
KIM, Baek Il [KR/KR]; (KR) (For US Only).
KWON, Ho Keun [KR/KR]; (KR) (For US Only).
LEE, Su Young [KR/KR]; (KR) (For US Only)
Inventors: HONG, Kug Sun; (KR).
JUNG, Hyun Suk; (KR).
RYU, Hyun Seung; (KR).
KIM, Baek Il; (KR).
KWON, Ho Keun; (KR).
LEE, Su Young; (KR)
Agent: LEE, Jae Hwa; 4th Floor Duckchun B/D. 718-10, Yoksam 1-dong Kangnam-ku Seoul 135-081 (KR)
Priority Data:
10-2009-0032743 15.04.2009 KR
Title (EN) TOOTHPASTE COMPOSITION FOR HYPERSENSITIVE-TEETH CONTAINING NANO-SIZED CARBONATE APATITE
(FR) COMPOSITION DE PÂTE DENTIFRICE CONTENANT DES NANOPARTICULES DE CARBONATE APATITE POUR DENTS HYPERSENSIBLES
(KO) 나노크기의 탄산아파타이트를 함유하는 지각과민성 치아용 치약 조성물
Abstract: front page image
(EN)The present invention relates to a toothpaste composition containing nano-sized carbonate apatite particles, which alleviates pain in patients with hypersensitive-teeth (cold temperature sensitivity), and provides a toothpaste composition for hypersensitive-teeth containing an active ingredient prepared by mixing silica and carbonate apatite particles with an average diameter of 1nm~500nm, in a weight ratio of 1:0.5 to 20. According to the present invention, nano-sized carbonate apatite particles mixed with abrasive silica in an appropriate mixture ratio, effectively coat a tooth surface by resealing exposed dentinal tubules, have a high safety level as their physical and chemical composition is identical to that of teeth, and form a coating on the surface of teeth by simply brushing, and can therefore be used effectively by a person with damaged enamel.
(FR)Composition de pâte dentifrice contenant des nanoparticules de carbonate apatite qui apaise la douleur chez des patients à hypersensibilité dentaire (sensibilité au froid), dont le principe actif est obtenu en mélangeant de la silice et des particules de carbonate apatite d'un diamètre moyen de 1nm~500nm selon un rapport de poids de 1 :0,5 à 20. Selon la présente invention, les nanoparticules de carbonate apatite mélangées à de la silice selon un rapport approprié recouvrent efficacement la surface de la dent, obturent les tubules exposées de la dentine, ont un niveau d'innocuité élevé dans la mesure où leur compositions physique et chimique est la même que celle des dents, peuvent être appliquées sur la surface des dents au moyen d'une simple brosse et conviennent dont bien pour des personne chez qui l'émail des dents est endommagée.
(KO)본 발명은 지각과민성 치아(시린이) 환자들에게 시린이 완화 효과가 있는 나노크기의 탄산아파타이트를 함유한 치약 조성물에 관한 것으로, 실리카와 1㎚∼500㎚의 평균입경을 갖는 탄산아파타이트를 1:0.5 내지 20의 중량비로 배합한 조성물을 유효성분으로 함유하는 치아의 지각과민 완화용 치약 조성물을 제공한다. 본 발명에 따르면, 실리카 연마제와 적정 배합비율로 혼합된 나노 탄산아파타이트는 노출된 상아세관을 다시 밀봉하는 차아 표면 코팅효과가 있고 치아를 구성하는 미네랄 성분과 물리, 화학적으로 동일하기 때문에 안전성이 높고 칫솔질만으로 치아 표면에 코팅층을 형성하기 때문에 치아 법랑질이 손상된 사람에게도 유용하게 적용이 가능하다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)