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1. (WO2010119992) DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/119992    International Application No.:    PCT/JP2010/057201
Publication Date: 21.10.2010 International Filing Date: 16.04.2010
IPC:
C07D 295/16 (2006.01), C07D 207/16 (2006.01), C07D 207/26 (2006.01), C07D 209/18 (2006.01), C07D 209/24 (2006.01), C07D 209/42 (2006.01), C07D 211/22 (2006.01), C07D 211/34 (2006.01), C07D 211/46 (2006.01), C07D 211/58 (2006.01), C07D 211/76 (2006.01), C07D 211/88 (2006.01), C07D 213/61 (2006.01), C07D 213/65 (2006.01), C07D 213/70 (2006.01)
Applicants: TAKEDA PHARMACEUTICAL COMPANY LIMITED [JP/JP]; 1-1, Doshomachi 4-chome, Chuo-ku, Osaka-shi, Osaka 5410045 (JP) (For All Designated States Except US).
KASAI, Shizuo [JP/JP]; (JP) (For US Only).
MCGEE, JR., Kevin Francis [US/US]; (US) (For US Only)
Inventors: KASAI, Shizuo; (JP).
MCGEE, JR., Kevin Francis; (US)
Agent: TAKASHIMA, Hajime; Meiji Yasuda Seimei Osaka Midosuji Bldg., 1-1, Fushimimachi 4-chome, Chuo-ku, Osaka-shi, Osaka 5410044 (JP)
Priority Data:
61/202,886 16.04.2009 US
Title (EN) DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES
(FR) DÉRIVÉS DE N-ACYL-N'-PHÉNYLPIPÉRAZINE UTILES (NOTAMMENT) POUR LA PRÉVENTION OU LE TRAITEMENT DU DIABÈTE
Abstract: front page image
(EN)The present invention relates to a compound represented by the formula wherein each symbol is as defined in the present specification, which has a superior RBP4-lowering action and is useful as a pharmaceutical composition for the prophylaxis or treatment of a disease or condition mediated by an increase in RBP4.
(FR)La présente invention concerne un composé représenté par la formule ci-après, dans laquelle chaque symbole est tel que défini dans la présente spécification, ce composé présentant une excellente activité de baisse du taux de RBP4 et étant utile en tant que composition pharmaceutique pour la prévention ou le traitement d'une maladie ou d'une affection médiée par une augmentation de RBP4.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)