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1. (WO2010118274) PREPARATION OF 6-KETO, 3-ALKOXY MORPHINANS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2010/118274 International Application No.: PCT/US2010/030453
Publication Date: 14.10.2010 International Filing Date: 09.04.2010
IPC:
C07D 489/02 (2006.01)
Applicants: HAAR JR., Joseph, P.[US/US]; US (UsOnly)
ROESCH, Kevin, R.[US/US]; US (UsOnly)
GINDELBERGER, David, E.[US/US]; US (UsOnly)
MALLINCKRODT INC.[US/US]; 675 McDonnell Boulevard Hazelwood, Missouri 63042, US (AllExceptUS)
Inventors: HAAR JR., Joseph, P.; US
ROESCH, Kevin, R.; US
GINDELBERGER, David, E.; US
Agent: SIMAN, Craig, D.; Mallinckrodt Inc. 675 McDonnell Boulevard Hazelwood, Missouri 63042, US
Priority Data:
61/167,87609.04.2009US
61/247,01530.09.2009US
Title (EN) PREPARATION OF 6-KETO, 3-ALKOXY MORPHINANS
(FR) PRÉPARATION DE 6-CÉTO, 3-ALCOXY MORPHINANES
Abstract: front page image
(EN) The present invention provides processes for the preparation of saturated 6-keto. 3-alkoxy morphinans from unsaturated 6-hydroxy, 3-hydroxy morphinans. In particular, the invention provides processes that utilize catalytic isomerization and alkylation reaclions for the preparation of saturated 6-keto, 3-alkoxy morphinans.
(FR) La présente invention porte sur des procédés de préparation de 6-céto saturé, 3-alcoxy morphinanes à partir de 6-hydroxy insaturé, 3-hydroxy morphinanes. En particulier, l'invention porte sur des procédés qui utilisent des réactions d'isomérisation catalytique et d'alkylation pour la préparation de 6-céto saturé, 3-alcoxy morphinanes.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)