Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2010118207) PYRAZOLO [1, 5-A] PYRIMIDINE DERIVATIVES AS MTOR INHIBITORS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/118207 International Application No.: PCT/US2010/030350
Publication Date: 14.10.2010 International Filing Date: 08.04.2010
IPC:
C07D 487/04 (2006.01) ,C07D 519/00 (2006.01) ,A61K 31/519 (2006.01) ,A61P 35/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
487
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
519
Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/ or C07D455/257
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519
ortho- or peri-condensed with heterocyclic rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
SCHERING CORPORATION [US/US]; 2000 Galloping Hill Road Kenilworth, New Jersey 07033, US (AllExceptUS)
DENG, Yongqi [US/US]; US (UsOnly)
SUN, Binyuan [CN/US]; US (UsOnly)
ZENG, Hongbo [CN/US]; US (UsOnly)
RICHARDS, Matthew [US/US]; US (UsOnly)
SHIPPS, Gerald, W., Jr. [US/US]; US (UsOnly)
CHENG, Cliff, C. [CN/US]; US (UsOnly)
ZHAO, Yinyan [CN/US]; US (UsOnly)
MCRINER, Andrew [GB/US]; US (UsOnly)
MENG, Zhaoyang [CN/US]; US (UsOnly)
NAN, Yang [US/US]; US (UsOnly)
PATEL, Mehul, F. [US/US]; US (UsOnly)
WRONA, Iwona, E. [US/US]; US (UsOnly)
REDDY, Panduranga, Adulla [US/US]; US (UsOnly)
EKLOV, Brian, M. [US/US]; US (UsOnly)
TANG, Shuyi [CN/US]; US (UsOnly)
LIU, Duan [CN/US]; US (UsOnly)
MANDAL, Amit, K. [IN/US]; US (UsOnly)
ZHAO, Lianyun [CN/US]; US (UsOnly)
SIDDIQUI, M., Arshad [CA/US]; US (UsOnly)
Inventors:
DENG, Yongqi; US
SUN, Binyuan; US
ZENG, Hongbo; US
RICHARDS, Matthew; US
SHIPPS, Gerald, W., Jr.; US
CHENG, Cliff, C.; US
ZHAO, Yinyan; US
MCRINER, Andrew; US
MENG, Zhaoyang; US
NAN, Yang; US
PATEL, Mehul, F.; US
WRONA, Iwona, E.; US
REDDY, Panduranga, Adulla; US
EKLOV, Brian, M.; US
TANG, Shuyi; US
LIU, Duan; US
MANDAL, Amit, K.; US
ZHAO, Lianyun; US
SIDDIQUI, M., Arshad; US
Agent:
SU, Li; Merck & Co., Inc. 126 East Lincoln Avenue Rahway, NJ 07065, US
Priority Data:
61/168,09309.04.2009US
Title (EN) PYRAZOLO [1, 5-A] PYRIMIDINE DERIVATIVES AS MTOR INHIBITORS
(FR) DÉRIVÉS PYRAZOLO[1, 5-A]PYRIMIDINE EN TANT QU'INHIBITEURS DE MTOR
Abstract:
(EN) The present invention provides methods for inhibiting mTOR using pyrazolo[1,5-a]pyrimidine compounds and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with mTOR using such compounds.
(FR) La présente invention porte sur des procédés d'inhibition de mTOR à l'aide de composés pyrazolo[1, 5-A]pyrimidine et sur des procédés de traitement, de prévention, d'inhibition ou d'amélioration d'une ou plusieurs maladies associées à mTOR à l'aide de tels composés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2417138US20120114739