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1. (WO2010117287) A VIRUS-LIKE PARTICLE VECTOR FOR DELIVERY OF PHARMACEUTICAL AGENTS, A PROCESS FOR THE MANUFACTURE THEREOF, ITS USES AND A PHARMACEUTICAL COMPOSITION.

Pub. No.:    WO/2010/117287    International Application No.:    PCT/PL2010/000026
Publication Date: Fri Oct 15 01:59:59 CEST 2010 International Filing Date: Sat Apr 10 01:59:59 CEST 2010
IPC: A61K 47/48
A61K 9/50
A61P 31/04
C07K 14/075
Applicants: Instytut Bio chemii i Biofizki PAN
SZOLAJSKA, Ewa
CHROBOCZEK, Jadwiga
ZOCHOWSKA, Monika
Inventors: SZOLAJSKA, Ewa
CHROBOCZEK, Jadwiga
ZOCHOWSKA, Monika
Title: A VIRUS-LIKE PARTICLE VECTOR FOR DELIVERY OF PHARMACEUTICAL AGENTS, A PROCESS FOR THE MANUFACTURE THEREOF, ITS USES AND A PHARMACEUTICAL COMPOSITION.
Abstract:
The embodiment of the invention is a virus-like particle vector, a process for the manufacture thereof, use of the virus-like particle vector and a pharmaceutical composition, which contains the virus-like particle vector. The vector is intended for the delivery of therapeutic agents into specific mammalian tissues, especially low molecular weight agents, in particular low molecular weight anti-cancer drugs into cancer tissues. More specifically, the invention relates to the virus-like particle vector, which constitutes an adenoviral dodecahedron with the therapeutic substance encapsulated or covalently linked.