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1. (WO2010116550) METHOD FOR TESTING SENSITIVITY OF TUMOR TISSUE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/116550    International Application No.:    PCT/JP2009/067444
Publication Date: 14.10.2010 International Filing Date: 30.09.2009
IPC:
A61K 31/18 (2006.01), A61K 31/343 (2006.01), A61K 31/404 (2006.01), A61K 31/498 (2006.01), A61P 35/00 (2006.01), A61K 49/00 (2006.01), G01N 33/15 (2006.01), G01N 33/50 (2006.01)
Applicants: EISAI R&D MANAGEMENT CO., LTD. [JP/JP]; 6-10, Koishikawa 4-chome, Bunkyo-ku, Tokyo 1128088 (JP) (For All Designated States Except US).
FUNAHASHI, Yasuhiro [JP/JP]; (JP) (For US Only).
SEMBA, Taro [JP/JP]; (JP) (For US Only)
Inventors: FUNAHASHI, Yasuhiro; (JP).
SEMBA, Taro; (JP)
Agent: KOBAYASHI, Hiroshi; (JP)
Priority Data:
2009-083275 30.03.2009 JP
Title (EN) METHOD FOR TESTING SENSITIVITY OF TUMOR TISSUE
(FR) PROCÉDÉ DE TEST DE SENSIBILITÉ DE TISSU DE TUMEUR
(JA) 腫瘍組織の感受性を検査する方法
Abstract: front page image
(EN)Disclosed is a method for testing the sensitivity of a tumor tissue to a sulfonamide compound. Specifically disclosed is a method for testing the sensitivity of a tumor tissue to a sulfonamide compound, which comprises the steps of measuring Ktarns values in a tumor tissue collected from a subject before and after the sulfonamide compound or an analogue thereof is administered to the subject and analyzing the distribution of the Ktrans values before and after the administration.
(FR)L'invention porte sur un procédé de test de la sensibilité d'un tissu de tumeur vis-à-vis d'un composé de sulfonamide. De façon spécifique, l'invention porte sur un procédé de test de la sensibilité d'un tissu de tumeur à un composé de sulfonamide, lequel procédé comprend les étapes consistant à mesurer des valeurs Ktarns dans un tissu de tumeur collecté à partir d'un sujet avant et après que le composé sulfonamide ou un analogue de celui-ci ait été administré au sujet et à analyser la répartition des valeurs Ktarns avant et après l'administration.
(JA) 本発明は、スルホンアミド化合物に対する腫瘍組織の感受性を検査する方法の提供を目的とする。  本発明は、スルホンアミド化合物またはその類縁体を被検者に投与する前および投与した後の被検者 の腫瘍組織におけるKtrans値を測定し、当該投与前後のKtrans値の分布を解析する工程を含む、スルホ ンアミド化合物に対する前記腫瘍組織の感受性を検査する方法を提供する。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)