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1. WO2010115984 - METHOD FOR POLYPEPTIDE TRANSFER INTO CELLS

Publication Number WO/2010/115984
Publication Date 14.10.2010
International Application No. PCT/EP2010/054711
International Filing Date 09.04.2010
IPC
G01N 33/50 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
CPC
A61K 38/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
02Peptides of undefined number of amino acids; Derivatives thereof
A61P 31/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 37/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
02Immunomodulators
04Immunostimulants
C12N 5/0636
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor;
06Animal cells or tissues; Human cells or tissues
0602Vertebrate cells
0634Cells from the blood or the immune system
0636T lymphocytes
G01N 33/56911
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
569for microorganisms, e.g. protozoa, bacteria, viruses
56911Bacteria
Applicants
  • LOPHIUS BIOSCIENCES GMBH [DE]/[DE] (AllExceptUS)
  • BARABAS, Sascha [DE]/[DE] (UsOnly)
  • EDMAIER, Katrin [DE]/[DE] (UsOnly)
  • DEML, Ludwig [DE]/[DE] (UsOnly)
Inventors
  • BARABAS, Sascha
  • EDMAIER, Katrin
  • DEML, Ludwig
Agents
  • DEHMEL, Albrecht
Priority Data
09157777.509.04.2009EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD FOR POLYPEPTIDE TRANSFER INTO CELLS
(FR) PROCÉDÉ DE TRANSFERT DE POLYPEPTIDES DANS DES CELLULES
Abstract
(EN)
The present invention relates to a method for polypeptide transfer into cells. The present invention further relates to the detection of polypeptide-specific immune cells and the priming, expansion and reactivation of polypeptide-specific T cells. Moreover the present invention relates to polypeptides of the methods of the present invention in combination with urea and their use for research, diagnosis or treatment and prevention of diseases in animals and humans.
(FR)
La présente invention concerne un procédé de transfert de polypeptides dans des cellules. L'invention concerne en outre la détection de cellules immunitaires spécifiques des polypeptides et l'amorçage, l'expansion et la réactivation de lymphocytes T spécifiques des polypeptides. En outre, la présente invention concerne des polypeptides des procédés de la présente invention en association avec l'urée et leur utilisation pour la recherche, le diagnostic ou le traitement et la prévention de maladies chez les animaux et les êtres humains.
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