Search International and National Patent Collections

1. (WO2010115252) PHTHALIMIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY COMPOUNDS AND/OR TNF-α MODULATORS, METHOD FOR PRODUCING SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USES THEREOF FOR THE TREATMENT OF INFLAMMATORY DISEASES

Pub. No.:    WO/2010/115252    International Application No.:    PCT/BR2010/000099
Publication Date: Fri Oct 15 01:59:59 CEST 2010 International Filing Date: Thu Apr 08 01:59:59 CEST 2010
IPC: C07D 209/48
C07D 209/28
C07C 229/42
C07C 229/40
C07C 57/40
C07C 65/10
C07C 65/34
C07C 209/28
C07C 245/08
A61K 31/4035
A61K 31/196
A61K 31/192
A61K 31/60
A61K 31/405
A61K 31/655
A61K 31/635
A61P 29/00
A61P 7/02
Applicants: EMS S.A.
Universidade Estadual Paulista Julio de Mesquita Filho - UNESP
SANTOS, Jean Leandro dos Santos
VIZIOLI, Ednir de Oliveira
CHIN, Chung Man
MENEGON, Renato Farina
BLAU, Lorena
Inventors: SANTOS, Jean Leandro dos Santos
VIZIOLI, Ednir de Oliveira
CHIN, Chung Man
MENEGON, Renato Farina
BLAU, Lorena
Title: PHTHALIMIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY COMPOUNDS AND/OR TNF-α MODULATORS, METHOD FOR PRODUCING SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USES THEREOF FOR THE TREATMENT OF INFLAMMATORY DISEASES
Abstract:
The present invention relates to phthalimide derivatives of non-steroidal anti-inflammatory compounds and/or TNF-α modulators, to a method for producing these derivatives, to pharmaceutical compositions containing these derivatives, and to uses thereof, including the use for the treatment of inflammatory diseases, in particular those associated with chronic inflammatory conditions, such as rheumatoid arthritis, and inflammatory intestinal diseases (such as Crohn's disease), and to the use of these compositions as antipyretics, analgesics and platelet aggregation inhibitors.