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Machine translation
1. (WO2010115141) SYSTEM AND USES FOR GENERATING DATABASES OF PROTEIN SECONDARY STRUCTURES INVOLVED IN INTER-CHAIN PROTEIN INTERACTIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/115141    International Application No.:    PCT/US2010/029835
Publication Date: 07.10.2010 International Filing Date: 02.04.2010
IPC:
G06F 17/00 (2006.01), G06F 17/40 (2006.01), G06F 19/00 (2011.01)
Applicants: NEW YORK UNIVERSITY [US/US]; 70 Washington Square New York, NY 10012 (US) (For All Designated States Except US)
Inventors: JOCHIM, Andrea, L.; (US).
ARORA, Paramjit, S.; (US)
Agent: CHILDS, Carissa, R.; LeClairRyan 290 Linden Oaks, Suite 310 Rochester, NY 14625 (US)
Priority Data:
61/166,211 02.04.2009 US
Title (EN) SYSTEM AND USES FOR GENERATING DATABASES OF PROTEIN SECONDARY STRUCTURES INVOLVED IN INTER-CHAIN PROTEIN INTERACTIONS
(FR) SYSTÈME ET UTILISATIONS POUR LA GÉNÉRATION DE BANQUES DE DONNÉES DE STRUCTURES SECONDAIRES DE PROTÉINES, IMPLIQUÉES DANS LES INTERACTIONS INTERCHAÎNE DES PROTÉINES
Abstract: front page image
(EN)The present invention relates to methods and systems for generating a database of protein secondary structures that are at an interface of a two-chain inter- protein interaction. Collections of secondary structures identified according to the methods disclosed herein, and their use in identifying therapeutic drug candidates potentially effective in modulating a two-chain inter-protein interaction having a secondary structure at its interface, are also disclosed.
(FR)La présente invention concerne des procédés et des systèmes pour la génération d'une banque de données de structures secondaires de protéines, lesquelles se trouvent à l'interface d'une interaction entre deux chaînes protéiques. L'invention concerne également les ensembles de structures secondaires identifiées par les procédés décrits ici, et leur utilisation dans l'identification de candidats pour des médicaments thérapeutiques, potentiellement efficaces pour moduler des interactions entre deux chaînes protéiques ayant une structure secondaire à l'interface.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)