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1. (WO2010115122) GENERATION OF UNIFORM FRAGMENTS OF NUCLEIC ACIDS USING PATTERNED SUBSTRATES
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2010/115122 International Application No.: PCT/US2010/029807
Publication Date: 07.10.2010 International Filing Date: 02.04.2010
IPC:
C12Q 1/68 (2006.01) ,C07H 21/02 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
21
Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
02
with ribosyl as saccharide radical
Applicants:
GUNDERSON, Kevin [US/US]; US (UsOnly)
LEBL, Michael [CZ/US]; US (UsOnly)
HEINER, David, L. [US/US]; US (UsOnly)
ILLUMINA, INC. [US/US]; 9885 Towne Centre Drive San Diego, California 92121, US (AllExceptUS)
Inventors:
GUNDERSON, Kevin; US
LEBL, Michael; US
HEINER, David, L.; US
Agent:
SCHULMAN, Robert, M.; Hunton & Williams Intellectual Property Department 1900 K Street, N.W. Washington, District of Columbia 20006, US
Priority Data:
61/166,35603.04.2009US
Title (EN) GENERATION OF UNIFORM FRAGMENTS OF NUCLEIC ACIDS USING PATTERNED SUBSTRATES
(FR) GÉNÉRATION DE FRAGMENTS UNIFORMES D'ACIDES NUCLÉIQUES EN UTILISANT DES SUBSTRATS À MOTIFS
Abstract:
(EN) Methods of generating nucleic acid fragments of substantially uniform length from sample nucleic acids comprising linearly stretching the sample nucleic acids over a substrate having a plurality of cleavage regions separated by relatively consistent distances, cleaving the linearly stretched sample nucleic acids at the cleavage regions, and collecting the resulting nucleic acid fragments. The method may further include collecting and concentrating the resultant nucleic acid fragments of substantially uniform length.
(FR) L'invention concerne des procédés de génération de fragments d'acide nucléique, de longueur sensiblement uniforme, à partir d'acides nucléiques échantillons, comprenant l'étirage linéaire des acides nucléiques échantillons sur un substrat présentant une série de régions de clivage, séparées par des distances relativement uniformes, le clivage des acides nucléiques échantillons étirés de manière linéaire au niveau des régions de clivage, et la collecte des fragments résultants d'acide nucléique. Le procédé peut comprendre en outre, la collecte et la concentration des fragments résultants d'acide nucléique ayant une longueur sensiblement uniforme.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)