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1. (WO2010115008) OCULAR SURFACE INTERFEROMETRY (OSI) DEVICES, SYSTEMS, AND METHODS FOR IMAGING, PROCESSING, AND/OR DISPLAYING AN OCULAR TEAR FILM AND/OR MEASURING OCULAR TEAR FILM LAYER THICKNESS (ES)

Pub. No.:    WO/2010/115008    International Application No.:    PCT/US2010/029645
Publication Date: Fri Oct 08 01:59:59 CEST 2010 International Filing Date: Fri Apr 02 01:59:59 CEST 2010
IPC: A01N 57/26
Applicants: TEARSCIENCE, INC.
KORB, Donald, R.
WEBER, William, L.
CHINNOCK, Randal, B.
GRAVELY, Benjamin, T.
GRENON, Steven, M.
Inventors: KORB, Donald, R.
WEBER, William, L.
CHINNOCK, Randal, B.
GRAVELY, Benjamin, T.
GRENON, Steven, M.
Title: OCULAR SURFACE INTERFEROMETRY (OSI) DEVICES, SYSTEMS, AND METHODS FOR IMAGING, PROCESSING, AND/OR DISPLAYING AN OCULAR TEAR FILM AND/OR MEASURING OCULAR TEAR FILM LAYER THICKNESS (ES)
Abstract:
Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image.