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1. (WO2010112194) ANTIGEN-BINDING POLYPEPTIDES AND MULTISPECIFIC ANTIBODIES COMPRISING THEM

Pub. No.:    WO/2010/112194    International Application No.:    PCT/EP2010/002008
Publication Date: Fri Oct 08 01:59:59 CEST 2010 International Filing Date: Wed Mar 31 01:59:59 CEST 2010
IPC: C07K 16/00
C07K 16/28
Applicants: F. HOFFMANN-LA ROCHE AG
KLEIN, Christian
SCHAEFER, Wolfgang
Inventors: KLEIN, Christian
SCHAEFER, Wolfgang
Title: ANTIGEN-BINDING POLYPEPTIDES AND MULTISPECIFIC ANTIBODIES COMPRISING THEM
Abstract:
The present invention relates to relates to antigen-binding polypetides comprising a) VH-CL-linker-VL-CH1 or b) VL-CH1-linker-VH-CL and especially to multispecific antibodies comprising such polypetides, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.