WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2010112194) ANTIGEN-BINDING POLYPEPTIDES AND MULTISPECIFIC ANTIBODIES COMPRISING THEM
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/112194    International Application No.:    PCT/EP2010/002008
Publication Date: 07.10.2010 International Filing Date: 30.03.2010
IPC:
C07K 16/00 (2006.01), C07K 16/28 (2006.01)
Applicants: F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124 CH-4070 Basel (CH) (For All Designated States Except US).
KLEIN, Christian [DE/CH]; (CH) (For US Only).
SCHAEFER, Wolfgang [DE/DE]; (DE) (For US Only)
Inventors: KLEIN, Christian; (CH).
SCHAEFER, Wolfgang; (DE)
Agent: BURGER, Alexander; Roche Diagnostics GmbH Patent Department (TR-E) Postfach 11 52 82372 Penzberg (DE)
Priority Data:
09004901.6 02.04.2009 EP
Title (EN) ANTIGEN-BINDING POLYPEPTIDES AND MULTISPECIFIC ANTIBODIES COMPRISING THEM
(FR) POLYPEPTIDES SE LIANT À UN ANTIGÈNE ET ANTICORPS MULTISPÉCIFIQUES LES RENFERMANT
Abstract: front page image
(EN)The present invention relates to relates to antigen-binding polypetides comprising a) VH-CL-linker-VL-CH1 or b) VL-CH1-linker-VH-CL and especially to multispecific antibodies comprising such polypetides, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
(FR)La présente invention porte sur des polypeptides se liant à un antigène renfermant a) VH-CL-liant-VL-CH1 ou b) VL-CH1-liant-VH-CL et notamment sur des anticorps multispécifiques renfermant de tels polypeptides, sur leurs procédés de production, sur des compositions pharmaceutiques contenant lesdits anticorps et sur leurs utilisations.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)