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1. (WO2010111905) PHARMACEUTICAL COMPOSITION FOR TREATMENT OF 2 TYPE DABETES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/111905    International Application No.:    PCT/CN2010/070910
Publication Date: 07.10.2010 International Filing Date: 08.03.2010
IPC:
C07D 487/04 (2006.01), A61K 31/495 (2006.01), A61K 31/4985 (2006.01), A61K 31/155 (2006.01), A61K 9/20 (2006.01), A61P 3/10 (2006.01)
Applicants: JIANGSU HENGRUI MEDICINE CO., LTD. [CN/CN]; No.145 East Renmin Road, Xinpu District Lianyungang, Jiangsu 222002 (CN) (For All Designated States Except US).
YUAN, Kaihong [CN/CN]; (CN) (For US Only).
SUN, Piaoyang [CN/CN]; (CN) (For US Only)
Inventors: YUAN, Kaihong; (CN).
SUN, Piaoyang; (CN)
Agent: GE CHENG & CO., LTD.; Level 19, Tower E3, The Towers, Oriental Plaza No.1, East Chang An Avenue, Dongcheng District Beijing 100738 (CN)
Priority Data:
200910129595.X 31.03.2009 CN (Priority Withdrawn 06.09.2011)
Title (EN) PHARMACEUTICAL COMPOSITION FOR TREATMENT OF 2 TYPE DABETES
(FR) COMPOSITION PHARMACEUTIQUE SERVANT A TRAITER LE DIABETE DE TYPE 2
(ZH) 治疗2型糖尿病的药物组合物
Abstract: front page image
(EN)The present invention provides a pharmaceutical composition for the treatment of 2 type diabetes, wherein the pharmaceutical composition contains (R)-7-[3-amino- 4-(2,4,5-trifluoro-phenyl)-butyryl]-3-trifluoromethyl-5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine-1-carboxylic acid methyl ester or its pharmaceutically acceptable salts and metformin or its pharmaceutically acceptable salts (such as hydrochlorate), preparation method thereof and method of treating 2 type diabetes with the composition.
(FR)L'invention concerne une composition pharmaceutique servant à traiter le diabète de type 2. Cette composition contient un ester de méthyle d'acide (R)-7-[3-amino-4-(2,4,5-trifluoro-phényl)-butyryl]-3-trifluorométhyl-5,6,7,8-tétrahydro-imidazo[1,5-a]pyrazine-1-carboxylique ou ses sels pharmaceutiquement acceptables et de la metformine ou ses sels pharmaceutiquement acceptables (tels qu'un hydrochlorate). L'invention concerne également un procédé de préparation de cette composition, ainsi qu'une méthode de traitement du diabète de type 2 au moyen de cette composition.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)