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1. WO2010106215 - AMINOCYCLITOL COMPOUNDS, PROCEDURE FOR THE OBTAINMENT AND USES THEREOF

Publication Number WO/2010/106215
Publication Date 23.09.2010
International Application No. PCT/ES2010/070164
International Filing Date 18.03.2010
IPC
C07C 233/36 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
233Carboxylic acid amides
01having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
34having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
35with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
36having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
C07H 5/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
5Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
04to nitrogen
CPC
A61P 1/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
04for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
A61P 1/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
16for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 11/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
06Antiasthmatics
A61P 19/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
02for joint disorders, e.g. arthritis, arthrosis
A61P 25/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
Applicants
  • CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) [ES]/[ES] (AllExceptUS)
  • UNIVERSIDAD AUTONÓMA DE BARCELONA [ES]/[ES] (AllExceptUS)
  • UNIVERSIDAD DE BARCELONA [ES]/[ES] (AllExceptUS)
  • LLEBARIA SOLDEVILLA, Amadeo [ES]/[ES] (UsOnly)
  • BEDIA GIRBÉS, Carmen [ES]/[ES] (UsOnly)
  • HARRAK SERIFI, Youssef [MA]/[ES] (UsOnly)
  • CASTAÑO GARCÍA, Angel Raul [ES]/[ES] (UsOnly)
  • BARRA QUAGLIA, Carolina Mercedes [AR]/[ES] (UsOnly)
  • DELGADO CIRILO, Antonio [ES]/[ES] (UsOnly)
Inventors
  • LLEBARIA SOLDEVILLA, Amadeo
  • BEDIA GIRBÉS, Carmen
  • HARRAK SERIFI, Youssef
  • CASTAÑO GARCÍA, Angel Raul
  • BARRA QUAGLIA, Carolina Mercedes
  • DELGADO CIRILO, Antonio
Agents
  • PONS ARIÑO, Angel
Priority Data
P 20090075520.03.2009ES
Publication Language Spanish (es)
Filing Language Spanish (ES)
Designated States
Title
(EN) AMINOCYCLITOL COMPOUNDS, PROCEDURE FOR THE OBTAINMENT AND USES THEREOF
(ES) COMPUESTOS AMINOCICLITOLES, PROCEDIMIENTO DE OBTENCIÓN Y USOS
(FR) COMPOSÉS AMINOCYCLITOLS, PROCÉDÉ D'OBTENTION ET UTILISATIONS
Abstract
(EN) Aminocyclitol compounds, procedure for the obtainment and uses thereof. Aminocyclitol compounds and uses thereof as pharmaceutical compositions for the treatment of diseases associated with alterations in iNKT cells, more specifically autoimmune diseases, cancer, infections caused by pathogenic microorganisms or inflammatory diseases. Furthermore the invention relates to the procedure for the obtainment of said compounds.
(ES) Compuestos aminociclitoles y sus usos como composiciones farmacéuticas para el tratamiento de enfermedades asociadas con alteraciones en las células iNKT, más concretamente a enfermedades autoinmunes, cáncer, infecciones causadas por microorganismos patógenos o enfermedades inflamatorias. Además, la invención se refiere al procedimiento de obtención de dichos compuestos.
(FR) L'invention concerne des composés aminocyclitols et leurs utilisations comme compositions pharmaceutiques dans le traitement de maladies associées à des altérations des cellules iNKT, telles que, notamment, les maladies autoimmunes, le cancer, les infections causées par des microorganismes pathogènes ou les maladies inflammatoires. Cette invention concerne, en outre, le procédé d'obtention desdits composés.
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