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1. WO2010096254 - MICROSPHERE/NANOFIBER COMPOSITES FOR DELIVERY OF DRUGS, GROWTH FACTORS, AND OTHER AGENTS

Publication Number WO/2010/096254
Publication Date 26.08.2010
International Application No. PCT/US2010/022573
International Filing Date 29.01.2010
IPC
A61L 31/12 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
31Materials for other surgical articles
12Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material
CPC
A61L 2300/414
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
2300Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
40characterised by a specific therapeutic activity or mode of action
412Tissue-regenerating or healing or proliferative agents
414Growth factors
A61L 2300/44
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
2300Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
40characterised by a specific therapeutic activity or mode of action
44Radioisotopes, radionuclides
A61L 2300/442
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
2300Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
40characterised by a specific therapeutic activity or mode of action
442Colorants, dyes
A61L 2300/45
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
2300Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
40characterised by a specific therapeutic activity or mode of action
45Mixtures of two or more drugs, e.g. synergistic mixtures
A61L 2300/604
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
2300Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
60characterised by a special physical form
602Type of release, e.g. controlled, sustained, slow
604Biodegradation
A61L 2300/622
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
2300Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
60characterised by a special physical form
62Encapsulated active agents, e.g. emulsified droplets
622Microcapsules
Applicants
  • THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA [US]/[US] (AllExceptUS)
  • MAUCK, Robert [US]/[US] (UsOnly)
  • IONESCU, Lara [US]/[US] (UsOnly)
  • BURDICK, Jason, Alan [US]/[US] (UsOnly)
  • BAKER, Brendon [US]/[US] (UsOnly)
Inventors
  • MAUCK, Robert
  • IONESCU, Lara
  • BURDICK, Jason, Alan
  • BAKER, Brendon
Agents
  • CALDWELL, John, W.
Priority Data
61/154,36621.02.2009US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MICROSPHERE/NANOFIBER COMPOSITES FOR DELIVERY OF DRUGS, GROWTH FACTORS, AND OTHER AGENTS
(FR) COMPOSITES MICROSPHÈRES/NANOFIBRES POUR ADMINISTRATION DE MÉDICAMENTS, FACTEURS DE CROISSANCE ET AUTRES AGENTS
Abstract
(EN)
Provided are compositions that include polymeric fibers and microspheres entrapped within the fibers, the compositions being capable of controlled delivery of one or more agents while also maintaining their structural properties. Also provided are related methods of fabricating these compositions and methods of utilizing the compositions to deliver agents to a subject.
(FR)
L'invention porte sur des compositions comprenant des fibres polymères et des microsphères piégées à l'intérieur des fibres, les compositions étant capables d'une administration contrôlée d'un ou plusieurs agents tout en maintenant et conservant également leurs propriétés structurales. L'invention porte également sur des procédés liés de fabrication de ces compositions et sur des procédés d'utilisation des compositions pour administration d'agents à un sujet.
Also published as
Latest bibliographic data on file with the International Bureau