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1. WO2010086864 - METHODS AND COMPOSITIONS FOR TREATING ALZHEIMER'S DISEASE

Publication Number WO/2010/086864
Publication Date 05.08.2010
International Application No. PCT/IL2010/000088
International Filing Date 01.02.2010
IPC
A61K 31/575 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
575substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
A61P 25/28 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
28for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
CPC
A61K 31/575
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids
575substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
Applicants
  • GALMED INTERNATIONAL LTD. [MT]/[MT] (AllExceptUS)
  • GILAT, Tuvia [IL]/[IL] (UsOnly)
  • ANGEL, Itzchak [IL]/[IL] (UsOnly)
Inventors
  • GILAT, Tuvia
  • ANGEL, Itzchak
Agents
  • WEBB, Cynthia
Priority Data
61/149,10002.02.2009US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS AND COMPOSITIONS FOR TREATING ALZHEIMER'S DISEASE
(FR) PROCÉDÉS ET COMPOSITIONS DE TRAITEMENT DE LA MALADIE D'ALZHEIMER
Abstract
(EN)
The present invention relates to methods for treatment, prevention, and inhibition of progression of Alzheimer's disease, and other brain diseases characterized by amyloid plaque deposits, comprising the administration to a subject a bile acid fatty acid conjugates or bile salt fatty acid conjugate (FABAC).
(FR)
La présente invention concerne des procédés de traitement, de prévention, et d'inhibition de la progression de la maladie d'Alzheimer, et d'autres maladies cérébrales caractérisées par des dépôts de plaque amyloïde, qui comprennent l'administration à un sujet d'un conjugué d'acide biliaire et d'acide gras ou d'un conjugué de sel biliaire et d'acide gras (FABAC).
Also published as
Latest bibliographic data on file with the International Bureau