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1. (WO2010085119) BETA-GLUCAN-BASED SCAFFOLD FOR BIOLOGICAL TISSUE ENGINEERING USING RADIATION FUSION TECHNOLOGY, AND PRODUCTION METHOD THEREFOR
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/085119 International Application No.: PCT/KR2010/000430
Publication Date: 29.07.2010 International Filing Date: 22.01.2010
IPC:
A61L 27/36 (2006.01) ,C12N 13/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
36
containing ingredients of undetermined constitution or reaction products thereof
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
13
Treatment of micro-organisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
Applicants:
주식회사 큐젠바이오텍 QUEGEN BIOTECH CO., LTD. [KR/KR]; 경기도 시흥시 정왕1동 시화공단3가 101-1BL 한국생산기술연구원 창업보육센터 5동 211호 5-211 Kitech, 101-1BL Sihwagongdan-3-ga, Jeongwang1-dong, Siheung-si, Gyeonggi-do 429-931, KR (AllExceptUS)
송성기 SONG, Sung Ki [KR/KR]; KR (UsOnly)
장용만 JANG, Yong Man [KR/KR]; KR (UsOnly)
전인호 JEON, In Ho [KR/KR]; KR (UsOnly)
고상진 KO, Sang Jin [KR/KR]; KR (UsOnly)
전정란 JEON, Jeong Rhan [KR/KR]; KR (UsOnly)
전계택 CHUN, Gie Taek [KR/KR]; KR (UsOnly)
임윤목 LIM, Youn Mook [KR/KR]; KR (UsOnly)
권희정 KWON, Hui Jeong [KR/KR]; KR (UsOnly)
Inventors:
송성기 SONG, Sung Ki; KR
장용만 JANG, Yong Man; KR
전인호 JEON, In Ho; KR
고상진 KO, Sang Jin; KR
전정란 JEON, Jeong Rhan; KR
전계택 CHUN, Gie Taek; KR
임윤목 LIM, Youn Mook; KR
권희정 KWON, Hui Jeong; KR
Agent:
특허법인 이룸 ERUUM PATENT & LAW FIRM; 서울 강남구 대치동 1005-8 보성빌딩 5층 5F., Boseong Bldg., 1005-8 Daechi-dong, Kangnam-gu Seoul 135-851, KR
Priority Data:
10-2009-000534322.01.2009KR
10-2010-000591222.01.2010KR
Title (EN) BETA-GLUCAN-BASED SCAFFOLD FOR BIOLOGICAL TISSUE ENGINEERING USING RADIATION FUSION TECHNOLOGY, AND PRODUCTION METHOD THEREFOR
(FR) ECHAFAUDAGE À BASE DE BÊTA-GLUCANE POUR INGÉNIERIE TISSULAIRE BIOLOGIQUE AU MOYEN D'UNE TECHNIQUE DE FUSION PAR RAYONNEMENT, ET SON PROCÉDÉ DE PRODUCTION
(KO) 방사선 융합 기술을 이용한 생체조직공학용 베타-글루칸 기반 지지체 및 이의 제조방법
Abstract:
(EN) The present invention relates to a beta-glucan-based scaffold for biological tissue engineering using radiation fusion technology, and to a production method therefor. According to the production method of the present invention for beta-glucan-based scaffold, radiation fusion tissue engineering, a beta-glucan aqueous solution is cast and is then irradiated in a crosslinking reaction in such a way as to form a gel or solid scaffold, thereby facilitating cell attachment and making it easy to create a biomimetic environment conducive to the growth and differentiation of stem cells. Consequently, the beta-glucan-based scaffold according to the present invention can be usefully employed as a filler for tissue regeneration, cell culturing and plastic surgery, as a filler for voids in biological tissue, as a scaffold for reconstructive and corrective plastic surgery, and for cell transplantation and drug delivery.
(FR) L'invention concerne un échafaudage à base de bêta-glucane pour ingénierie tissulaire biologique au moyen d'une technique de fusion par rayonnement, et son procédé de production. Dans le procédé de production de l'échafaudage à base de bêta-glucane pour ingénierie tissulaire biologique au moyen d'une technique de fusion par rayonnement, une solution aqueuse de bêta-glucane est coulée, puis irradiée dans une réaction de réticulation afin de former un gel ou un échafaudage solide, ce qui facilite la fixation cellulaire et la création d'un environnement biomimétique conduisant à la croissance et à la différentiation de cellules souche. En conséquence, l'échafaudage à base de bêta-glucane de l'invention peut être utilisé comme charge pour la régénération tissulaire, la culture cellulaire et la chirurgie plastique, comme charge pour les vides dans un tissu biologique, et comme échafaudage pour la chirurgie plastique reconstructive et corrective et pour la transplantation cellulaire et l'administration de médicaments.
(KO) 본 발명은 방사선 융합 기술을 이용한 생체조직공학용 베타-글루칸 기반 지지체 및 이의 제조방법에 관한 것이다. 본 발명에 따른 방사선 융합 기술을 이용한 생체조직공학용 베타-글루칸 기반 지지체의 제조방법은, 베타-글루칸 수용액을 캐스팅한 후 방사선을 조사하여 가교반응을 수행하여 겔 또는 고체 형태의 지지체를 형성함으로써, 세포부착을 용이하게 하고, 줄기세포의 성장 및 분화에 효과적인 생체모방형 환경을 용이하게 구현할 수 있다. 따라서, 본 발명에 따른 베타-글루칸 기반 지지체는 조직 재생용, 세포 배양용, 성형용 충전제, 생체조직 빈공간용 충전제, 성형 보형물, 성형 보정물, 세포 이식용 및 약물전달용으로 유용하게 사용될 수 있다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)
Also published as:
JP2012515607US20110275795CN102292113