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1. (WO2010083611) METHOD FOR THE PREVENTION AND TREATMENT OF DIASTOLIC DYSFUNCTION EMPLOYING AN APOLIPOPROTEINA1 (APOA1) MIMETIC PEPTIDE/PHOSPHOLIPID COMPLEX
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/083611 International Application No.: PCT/CA2010/000108
Publication Date: 29.07.2010 International Filing Date: 25.01.2010
IPC:
A61K 38/17 (2006.01) ,A61P 9/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9
Drugs for disorders of the cardiovascular system
Applicants:
INSTITUT DE CARDIOLOGIE DE MONTREAL [CA/CA]; 5000 rue Bélanger Est Montréal, Québec H1T 1C8, CA (AllExceptUS)
TARDIF, Jean-Claude [CA/CA]; CA (UsOnly)
BUSSEUIL, David [CA/CA]; CA (UsOnly)
RHEAUME, Eric [CA/CA]; CA (UsOnly)
Inventors:
TARDIF, Jean-Claude; CA
BUSSEUIL, David; CA
RHEAUME, Eric; CA
Agent:
TESSIER, Louis; P.O. Box 54029 Town Mount-Royal, Quebec H3P 3H4, CA
Priority Data:
61/202,05123.01.2009US
61/202,19105.02.2009US
Title (EN) METHOD FOR THE PREVENTION AND TREATMENT OF DIASTOLIC DYSFUNCTION EMPLOYING AN APOLIPOPROTEINA1 (APOA1) MIMETIC PEPTIDE/PHOSPHOLIPID COMPLEX
(FR) PROCÉDÉ DE PRÉVENTION ET DE TRAITEMENT D'UN DYSFONCTIONNEMENT DIASTOLIQUE AU MOYEN D'UN COMPLEXE PEPTIDE/PHOSPHOLIPIDE MIMÉTIQUE DE L'APOLIPOPROTÉINE-A1 (APOA1)
Abstract:
(EN) A method of treating a diastolic dysfunction in a mammal comprising administering a therapeutically effective amount of a reverse lipid transport agonist to said mammal. The most preferred agonist is an Apolipoprotein-A1 (APO-A1) mimetic peptide/phospholipid complex.
(FR) L'invention porte sur un procédé de traitement d'un dysfonctionnement diastolique, chez un mammifère, qui comporte l'administration d'une quantité thérapeutiquement efficace d'un agoniste inverse de transport de lipide audit mammifère. L'agoniste idéal est un complexe peptide/phospholipide mimétique de l'apolipoprotéine-A1 (APOA1).
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2389189CA2788223