Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2010082134) COMBINATION ANTIBODIES FOR THE TREATMENT AND PREVENTION OF DISEASE CAUSED BY BACILLUS ANTHRACIS AND RELATED BACTERIA AND THEIR TOXINS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/082134 International Application No.: PCT/IB2010/000146
Publication Date: 22.07.2010 International Filing Date: 14.01.2010
IPC:
C07K 16/12 (2006.01) ,A61K 39/40 (2006.01) ,A61P 31/04 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
12
against material from bacteria
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
40
bacterial
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04
Antibacterial agents
Applicants:
IQ THERAPEUTICS BV [NL/NL]; Rosenburglaan 13a NL-9727 DL Groningen, NL (AllExceptUS)
GROEN, Herman [NL/NL]; NL (UsOnly)
Inventors:
GROEN, Herman; NL
Agent:
FINNIE, Isobel, Lara; Mintz Levin Cohn Ferris Glovsky and Popeo Intellectual Property LLP Alder Castle 10 Noble Street London EC2V 7JX, GB
Priority Data:
61/144,50714.01.2009US
Title (EN) COMBINATION ANTIBODIES FOR THE TREATMENT AND PREVENTION OF DISEASE CAUSED BY BACILLUS ANTHRACIS AND RELATED BACTERIA AND THEIR TOXINS
(FR) ANTICORPS COMBINÉS DESTINÉS AU TRAITEMENT ET À LA PRÉVENTION D'UNE MALADIE PROVOQUÉE PAR BACILLUS ANTHRACIS, AINSI QUE PAR LES BACTÉRIES CONNEXES ET PAR LEURS TOXINES
Abstract:
(EN) The invention relates to methods and compositions for the prevention and treatment of disease caused by B. anthracis or a bacterium which produces toxins or toxin components homologous to the virulence factors produced by B. anthracis or to the toxins or toxin components themselves, in the absence of bacteria. The methods and compositions of the invention comprise a combination of at least two antibodies, preferably monoclonal antibodies, most preferably human monoclonal antibodies, each of which binds with high affinity to a different bacterial antigen.
(FR) La présente invention concerne des procédés et compositions destinés à la prévention et au traitement d'une maladie provoquée par B. anthracis ou par une bactérie qui produit des toxines ou des composants de toxines homologues aux facteurs de virulence produits par B. anthracis, ou en l'absence des bactéries, par les toxines ou par les composants des toxines eux-mêmes. Les procédés et compositions de l'invention comprennent une combinaison d'au moins deux anticorps, de préférence des anticorps monoclonaux, et plus préférablement des anticorps monoclonaux humains, dont chacun se lie avec une haute affinité à un antigène bactérien différent.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2387584CA2749572