Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2010081898) NOVEL BENZOTRIAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF CNS DISORDERS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/081898 International Application No.: PCT/EP2010/050512
Publication Date: 22.07.2010 International Filing Date: 18.01.2010
IPC:
C07D 249/18 (2006.01) ,C07D 403/06 (2006.01) ,A61P 25/08 (2006.01) ,A61K 31/4192 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
249
Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
16
condensed with carbocyclic rings or ring systems
18
Benzotriazoles
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
403
Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/167
02
containing two hetero rings
06
linked by a carbon chain containing only aliphatic carbon atoms
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
08
Antiepileptics; Anticonvulsants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
4192
1,2,3-Triazoles
Applicants:
NeuroSearch A/S [DK/DK]; Pederstrupvej 93 DK-2750 Ballerup, DK (AllExceptUS)
NARDI, Antonio [IT/DE]; DE (UsOnly)
ERICHSEN, Helle Kirstein [DK/DK]; DK (UsOnly)
PETERS, Dan [SE/DK]; DK (UsOnly)
TROELSEN, Karin de Linde [DK/DK]; DK (UsOnly)
Inventors:
NARDI, Antonio; DE
ERICHSEN, Helle Kirstein; DK
PETERS, Dan; DK
TROELSEN, Karin de Linde; DK
Common
Representative:
NeuroSearch A/S; Pederstrupvej 93 DK-2750 Ballerup, DK
Priority Data:
PA 2009 0007219.01.2009DK
Title (EN) NOVEL BENZOTRIAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF CNS DISORDERS
(FR) NOUVEAUX DÉRIVÉS DE BENZOTRIAZOLE UTILES POUR LE TRAITEMENT DE TROUBLES DU SNC
Abstract:
(EN) The present invention relates to novel benzotriazole derivatives, efficacious in animal models of CNS disorders and, as such, valuable candidates for the prevention or treatment of CNS (Central Nervous System) diseases or disorders. In other aspects the invention relates to pharmaceutical compositions comprising the benzotriazole derivatives of the invention and to the use of these compounds for therapeutic applications.
(FR) La présente invention porte sur de nouveaux dérivés de benzotriazole, efficaces dans des modèles animaliers de troubles du SNC et qui sont, en soi, des candidats précieux pour la prévention ou le traitement de maladies ou troubles du SNC (système nerveux central). Dans d'autres aspects, l'invention porte sur des compositions pharmaceutiques comprenant le dérivé de quinolinone de l'invention et sur l'utilisation de ces composés pour des applications thérapeutiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2387568JP2012515191US20110275684