Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2010081878) MUTATED ANTITHROMBINS, A PROCESS FOR PREPARING THE SAME AND THEIR USE AS DRUGS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/081878 International Application No.: PCT/EP2010/050456
Publication Date: 22.07.2010 International Filing Date: 15.01.2010
IPC:
A61K 38/55 (2006.01) ,C07K 14/81 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
55
Protease inhibitors
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
81
Protease inhibitors
Applicants:
UNIVERSITE PARIS-SUD XI [FR/FR]; 15, rue Georges Clémenceau F-91405 Orsay Cedex, FR (AllExceptUS)
ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS [FR/FR]; 3, avenue Victoria F-75184 Paris Cedex 04, FR (AllExceptUS)
UNIVERSITE PARIS DESCARTES [FR/FR]; 12, rue de l'Ecole de Médecine F-75270 Paris Cedex 06, FR (AllExceptUS)
BORGEL born BOTBOL, Delphine [FR/FR]; FR (UsOnly)
FERGER born PICARD, Véronique [FR/FR]; FR (UsOnly)
BIANCHINI, Elsa [FR/FR]; FR (UsOnly)
LEROLLE, Nicolas [FR/FR]; FR (UsOnly)
DIEHL, Jean-Luc, René [FR/FR]; FR (UsOnly)
Inventors:
BORGEL born BOTBOL, Delphine; FR
FERGER born PICARD, Véronique; FR
BIANCHINI, Elsa; FR
LEROLLE, Nicolas; FR
DIEHL, Jean-Luc, René; FR
Agent:
GROSSET-FOURNIER, Chantal; Grosset-fournier & Demachy 54, rue Saint-Lazare F-75009 Paris, FR
Priority Data:
09290037.216.01.2009EP
Title (EN) MUTATED ANTITHROMBINS, A PROCESS FOR PREPARING THE SAME AND THEIR USE AS DRUGS
(FR) ANTITHROMBINES MUTÉES, LEURS PROCÉDÉS DE PRÉPARATION ET LEUR UTILISATION COMME MÉDICAMENTS
Abstract:
(EN) The present invention relates to the use of a composition comprising of at least a mutated antithrombin - having an anticoagulant activity substantially reduced with respect to the anticoagulant activity of the non mutated antithrombin, or - having no anticoagulant activity, for the preparation of a drug intended for the prevention or the treatment of pathologies associated with cellular injury, such as infection, inflammation or hypoxic injury.
(FR) La présente invention concerne l'utilisation d'une composition comprenant au moins une antithrombine mutée – présentant une activité anticoagulante sensiblement réduite par rapport à l'activité anticoagulante de l'antithrombine non mutée, ou – ne présentant aucune activité anticoagulante, pour la préparation d'un médicament destiné à la prévention ou au traitement de pathologies associées à une lésion cellulaire, comme une infection, une inflammation ou une lésion hypoxique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2379101JP2012515189US20120088715CA2749772