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1. (WO2010081662) METHODS FOR IDENTIFYING PATIENTS WHO WILL RESPOND WELL TO CANCER TREATMENT
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/081662 International Application No.: PCT/EP2010/000077
Publication Date: 22.07.2010 International Filing Date: 11.01.2010
IPC:
A61K 31/18 (2006.01) ,A61K 31/505 (2006.01) ,A61K 45/06 (2006.01) ,C12Q 1/68 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
16
Amides, e.g. hydroxamic acids
18
Sulfonamides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
TOPOTARGET A/S [DK/DK]; Smybion Science Park Fruebjergvej 3 DK-2100 København Ø, DK (AllExceptUS)
FAGERBERG, Jan [SE/SE]; SE (UsOnly)
Inventors:
FAGERBERG, Jan; SE
Agent:
MEWBURN ELLIS LLP; 33 Gutter Lane London EC2V 8AS, GB
Priority Data:
0900555.414.01.2009GB
61/205,12414.01.2009US
Title (EN) METHODS FOR IDENTIFYING PATIENTS WHO WILL RESPOND WELL TO CANCER TREATMENT
(FR) METHODES D'IDENTIFICATION DE PATIENTS SUSCEPTIBLES DE BIEN REAGIR A UN TRAITEMENT ANTICANCEREUX
Abstract:
(EN) The present invention relates to methods for identifying patients who will respond well to cancer treatment with a therapeutic regimen that comprises the use of a histone deacetylase inhibitor (HDACi) and one or more further chemotherapeutic agents. The invention also relates to methods of treating such patients with a therapeutic regimen comprising the use of a histone deacetylase inhibitor (HDACi) and one or more further chemotherapeutic agents.
(FR) L'invention concerne des méthodes destinées à identifier des patients susceptibles de bien réagir à un traitement anticancéreux au moyen d'un régime thérapeutique consistant à utiliser un inhibiteur d'histone désacétylase (HDACi) et au moins un autre agent chimiothérapeutique. L'invention concerne également des méthodes de traitement de ces patients au moyen d'un régime thérapeutique consistant à utiliser un inhibiteur d'histone désacétylase (HDACi) et au moins un autre chimiothérapeutique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
MXMX/a/2011/007373EP2387397JP2012515143CA2749051IN3350/KOLNP/2011