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1. (WO2010081112) PREVENTION AND/OR TREATMENT OF MULTIPLE ORGAN DYSFUNCTION SYNDROME WITH INTERLEUKIN-22
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/081112 International Application No.: PCT/US2010/020673
Publication Date: 15.07.2010 International Filing Date: 11.01.2010
IPC:
A61K 38/20 (2006.01) ,C07K 14/54 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
19
Cytokines; Lymphokines; Interferons
20
Interleukins
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
52
Cytokines; Lymphokines; Interferons
54
Interleukins (IL)
Applicants:
GENERON (SHANGHAI) CORPORATION [CN/CN]; Suite 302/303, Building 9, 1011 Ha Lei Road Z. J. Hi-Tech Park, Shanghai, China 201203, CN (AllExceptUS)
HUANG, Yu Liang [US/CN]; CN (UsOnly)
HUANG, Zhi Hua [CN/CN]; CN (UsOnly)
SUN, Qi [CN/CN]; CN (UsOnly)
Inventors:
HUANG, Yu Liang; CN
HUANG, Zhi Hua; CN
SUN, Qi; CN
Agent:
LUI, Jacqueline C.; 13/F, Bright Way Tower, 33 Mong Kok Road Mong Kok, Kowloon Hong Kong, CN
Priority Data:
61/144,13412.01.2009US
Title (EN) PREVENTION AND/OR TREATMENT OF MULTIPLE ORGAN DYSFUNCTION SYNDROME WITH INTERLEUKIN-22
(FR) PRÉVENTION ET/OU TRAITEMENT DU SYNDROME DE DÉFAILLANCE MULTIVISCÉRALE AVEC DE L'INTERLEUKINE 22
Abstract:
(EN) The present invention relates to use an agent for the prevention and/or treatment of multiple organ dysfunction syndrome (MODS) or multiple organ failure (MOF) comprising interleukin-22 (IL-22) as an effective ingredient. The present invention is applicable to prevention of or therapy for diseases from sepsis, septic shock, liver failure, to multiple organ dysfunction syndromes. More particularly, the present invention is useful for an emergency medical service, for treatment of injury caused by a traffic accident, burns, heat attacks, hypercytokinemia or severe infective diseases.
(FR) La présente invention concerne l'utilisation d'un agent pour la prévention et/ou le traitement du syndrome de défaillance multiviscérale ou d'une insuffisance polyviscérale, comprenant de l'interleukine 22 (IL‑22) en tant que principe actif. La présente invention s'applique à la prévention ou au traitement de maladies de la septicémie, du choc septique, de l'insuffisance hépatique aux syndromes de défaillance multiviscérale. De manière plus particulière, la présente invention est utile pour un service médical d'urgence, pour le traitement des lésions provoquées par un accident de la circulation, des brûlures, des crises cardiaques, d'une hypercytokinémie ou de maladies infectieuses sévères.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2385841JP2012515165US20110268696CN102348463CA2748392AU2010203446