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1. (WO2010080007) LIPOPROTEINS DERIVED FROM GRAM-POSITIVE BACTERIA FUNCTIONING AS TOLL-LIKE RECEPTOR 2 LIGAND
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/080007 International Application No.: PCT/KR2010/000164
Publication Date: 15.07.2010 International Filing Date: 11.01.2010
IPC:
C07K 14/47 (2006.01) ,C07K 14/775 (2006.01) ,A61P 37/04 (2006.01) ,G01N 33/53 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
775
Apolipopeptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
02
Immunomodulators
04
Immunostimulants
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
Applicants:
부산대학교 산학협력단 PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION [KR/KR]; 부산 금정구 장전동 산 30 부산대학교 Pusan National University, San 30, Jangjeon-dong, Geumjeong-gu Pusan 609-735, KR (AllExceptUS)
리까가쿠 켄큐쇼 THE INSTITUTE OF PHYSICAL AND CHEMICAL RESEARCH [JP/JP]; 사이타마현 와코시 히로사와 2-1 2-1, Hirosawa Wako , Saitama 351-0198, JP (AllExceptUS)
이복률 LEE, Bok Luel [KR/KR]; KR (UsOnly)
쿠로카와켄지 KUROKAWA, Kenji [JP/KR]; KR (UsOnly)
나카야마히로시 NAKAYAMA, Hiroshi [JP/JP]; JP (UsOnly)
아사누마미와코 ASANUMA, Miwako [JP/JP]; JP (UsOnly)
Inventors:
이복률 LEE, Bok Luel; KR
쿠로카와켄지 KUROKAWA, Kenji; KR
나카야마히로시 NAKAYAMA, Hiroshi; JP
아사누마미와코 ASANUMA, Miwako; JP
Agent:
김순웅 KIM, Soon Woong; 서울 구로구 구로동 188-5 키콕스벤처센터 209 209, KICOX Venture Center, 188-5, Guro-dong, Guro-gu Seoul 152-050, KR
Priority Data:
61/143,46709.01.2009US
Title (EN) LIPOPROTEINS DERIVED FROM GRAM-POSITIVE BACTERIA FUNCTIONING AS TOLL-LIKE RECEPTOR 2 LIGAND
(FR) LIPOPROTÉINES ISSUES DE BACTÉRIES À GRAM POSITIF FONCTIONNANT EN TANT QUE LIGANDS DES RÉCEPTEURS DE TYPE TOLL 2
(KO) Toll 유사수용체2 리간드로서 기능하는 그람양성균 유래의 리포단백질
Abstract:
(EN) The present invention provides lipoproteins derived from gram-positive bacteria functioning as a toll-like receptor 2 ligand. The lipoproteins derived from gram-positive bacteria act as a ligand bonded with the toll-like receptor 2. In addition, the lipoproteins can be provided as immunogens or immunostimulatory agents useful for the prevention or treatment of diseases caused by gram-positive bacteria, and also as an antibody for diagnosing gram-positive bacteria.
(FR) La présente invention concerne des lipoprotéines issues de bactéries à Gram positif fonctionnant en tant que ligands des récepteurs de type Toll2. Lesdites lipoprotéines issues de bactéries à Gram positif fonctionnent en tant que ligands liés aux récepteurs de type Toll2. En outre, lesdites lipoprotéines peuvent être utilisées sous la forme d'immunogènes ou d'agents immunostimulateurs utilisables en vue de la prévention ou du traitement de maladies provoquées par des bactéries à Gram positif et également en tant qu'anticorps en vue de diagnostiquer la présence de bactéries à Gram positif.
(KO) 본 발명에서는 Toll 유사 수용체2 에 리간드로서 기능하는 것을 특징으로 하는 그람양성균 (Gram-positive bacteria) 유래의 리포단백질을 제공하고자 한다. 상기 그람양성균 (Gram-positive bacteria) 유래의 리포단백질은 Toll like 수용체2 와 결합하는 리간드로서 작용하는 것으로 그람양성균으로 야기되는 질병을 예방 또는 치료하는 데 있어 좋은 면역원 또는 면역자극제로서 제공될 수 있으며, 그람양성균을 진단하는데 있어 진단용 항원으로 제공될 수 있다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)