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1. (WO2010079978) COMPOSITION FOR IMPROVING INFLAMMATORY DISEASE USING ABH ANTIGENS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/079978 International Application No.: PCT/KR2010/000103
Publication Date: 15.07.2010 International Filing Date: 07.01.2010
IPC:
A61K 48/00 (2006.01) ,A61K 31/7105 (2006.01) ,A61P 17/06 (2006.01) ,A61K 9/06 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7088
Compounds having three or more nucleosides or nucleotides
7105
Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17
Drugs for dermatological disorders
06
Antipsoriatics
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
06
Ointments; Bases therefor
Applicants:
서울대학교산학협력단 SNU R&DB Foundation [KR/KR]; 서울특별시 관악구 신림동 산 56-1 San 56-1 Sillim-dong, Gwanak-gu Seoul 151-742, KR (AllExceptUS)
오장희 OH, Jang Hee [KR/KR]; KR (UsOnly)
정지용 JUNG, Ji-Yong [KR/KR]; KR (UsOnly)
이동훈 LEE, Dong Hun [KR/KR]; KR (UsOnly)
이세라 LEE, Serah [KR/KR]; KR (UsOnly)
김연경 KIM, Yeon Kyung [KR/KR]; KR (UsOnly)
신정은 SHIN, Jeong-eun [KR/KR]; KR (UsOnly)
이현경 LEE, June Hyunkyung [US/KR]; KR (UsOnly)
정진호 CHUNG, Jin Ho [KR/KR]; KR (UsOnly)
Inventors:
오장희 OH, Jang Hee; KR
정지용 JUNG, Ji-Yong; KR
이동훈 LEE, Dong Hun; KR
이세라 LEE, Serah; KR
김연경 KIM, Yeon Kyung; KR
신정은 SHIN, Jeong-eun; KR
이현경 LEE, June Hyunkyung; KR
정진호 CHUNG, Jin Ho; KR
Agent:
특허법인 태평양 BAE, KIM & LEE IP GROUP; 서울특별시 서초구 서초2동 1329-7 신덕빌딩 11층 11th Floor, Shinduk Bldg., 1329-7 Seocho 2-dong, Seocho-gu Seoul 137-858, KR
Priority Data:
10-2009-000207809.01.2009KR
Title (EN) COMPOSITION FOR IMPROVING INFLAMMATORY DISEASE USING ABH ANTIGENS
(FR) COMPOSITION UTILISABLE POUR LE TRAITEMENT DE L'INFLAMMATION FAISANT APPEL À DES ANTIGÈNES ABH
(KO) ABH 항원을 이용한 염증질환 개선용 조성물
Abstract:
(EN) The present invention relates to a composition for improving inflammatory disease, and more specifically to a composition for improving inflammatory disease able to improve inflammatory reactions and the barrier function of epithelial tissue such as the skin, to enhance ageing resistance and skin elasticity and to prevent or treat ageing. The present invention makes it possible to control inflammatory reactions by modulating the expression and modulating the activity of ABH antigens, and thus the composition of the present invention can be employed as a development marker for therapeutic agents designed to soothe or treat or help in the treatment of diseases caused by inflammatory reaction in body tissue and notably the skin expressed by ABH antigens, and can be used in the development of external preparations and cosmetics containing external preparations designed for purposes such as restoration of normal function and moisturisation, wrinkle enhancement, whitening and elasticity recovery in skin through modulation of differentiation of keratinocytes and the skin barrier function.
(FR) La présente invention concerne une composition utilisable pour le traitement de l'inflammation et, plus précisément, une composition utilisable pour le traitement de l'inflammation capable d'entraîner une amélioration tant en ce qui concerne les réactions inflammatoires que la fonction barrière des tissus épithéliaux tels que la peau, capable aussi de renforcer la résistance au vieillissement et l'élasticité de la peau, ou, encore, de prévenir ou de traiter le vieillissement. La présente invention rend possible la lutte contre les réactions inflammatoires par modulation de l'expression et de l'activité des antigènes ABH, si bien que la composition selon la présente invention peut être utilisée en tant que marqueur de développement pour les agents thérapeutiques conçus pour calmer ou traiter ou contribuer au traitement de troubles provoqués par une réaction inflammatoire au sein des tissus corporels et, principalement, de la peau, s'exprimant par le biais des antigènes ABH. Ladite composition peut être utilisée dans le cadre de la mise au point de préparations réservées à la voie externe et de cosmétiques contenant des préparations réservées à la voie externe, conçues à des fins telles que la restauration d'une fonction normale et l'hydratation, l'atténuation des rides, le blanchiment et la restauration de l'élasticité de la peau grâce à la modulation de la différentiation des kératinocytes et de la fonction de la barrière cutanée.
(KO) 본 발명은 염증질환 개선용 조성물에 관한 것으로서, 보다 상세하게는 피부와 같은 상피 조직에서의 염증반응 및 장벽기능 개선과 항노화, 피부 탄력 강화 및 노화를 예방 또는 치료할 수 있는 염증질환 개선용 조성물에 관한 것이다. 본 발명에 따르면, ABH 항원의 발현 조절 및 활성 조절을 통해 염증반응을 제어할 수 있으므로, 본 발명의 조성물은 ABH 항원이 발현되는 피부를 비롯한 인체 조직에서의 염증반응이 원인이 되는 질환의 진정이나 치료 및 치료보조를 목적으로 하는 치료제의 개발 표적으로 활용할 수 있고, 또한 각질형성세포의 분화 및 피부장벽기능의 조절을 통한 피부의 정상기능 회복 및 보습, 주름개선, 미백, 탄력 회복 등을 목적으로 하는 외용제 및 외용제 성분을 포함하는 화장품의 개발에 사용될 수 있다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)
Also published as:
EP2377558JP2012514634US20110274707CN102355910US20140037773