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1. (WO2010079224) PHARMACEUTICAL COMPOSITION TO PROTECT AN ANIMAL AGAINST A DISORDER ARISING FROM AN INFECTION WITH A BACTERIUM THAT BELONGS TO THE GROUP OF NOCARDIOFORM ACTINOMYCETES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/079224 International Application No.: PCT/EP2010/050196
Publication Date: 15.07.2010 International Filing Date: 11.01.2010
IPC:
A61K 35/74 (2006.01) ,A61P 31/04 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
66
Materials from micro-organisms
74
Bacteria
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04
Antibacterial agents
Applicants:
INTERVET INTERNATIONAL B.V. [NL/NL]; Wim de Körverstraat 35 NL-5831 AN Boxmeer, NL (AllExceptUS)
JACOBS, Antonius Arnoldus Christiaan [NL/NL]; NL (UsOnly)
VAN DER GEIZE, Robert [NL/NL]; NL (UsOnly)
DIJKHUIZEN, Lubbert [NL/NL]; NL (UsOnly)
Inventors:
JACOBS, Antonius Arnoldus Christiaan; NL
VAN DER GEIZE, Robert; NL
DIJKHUIZEN, Lubbert; NL
Agent:
JANSSEN, P. J. P.; Wim de Körverstraat 35 NL-5831 AN Boxmeer, NL
Priority Data:
09150379.712.01.2009EP
61/143,86912.01.2009US
Title (EN) PHARMACEUTICAL COMPOSITION TO PROTECT AN ANIMAL AGAINST A DISORDER ARISING FROM AN INFECTION WITH A BACTERIUM THAT BELONGS TO THE GROUP OF NOCARDIOFORM ACTINOMYCETES
(FR) COMPOSITION PHARMACEUTIQUE DESTINÉE À PROTÉGER UN ANIMAL CONTRE UN TROUBLE CAUSÉ PAR UNE INFECTION PAR UNE BACTÉRIE APPARTENANT AU GROUPE DES ACTINOMYCÈTES NOCARDIOFORMES
Abstract:
(EN) The invention pertains to a pharmaceutical composition to protect an animal against a disorder arising from an infection with a bacterium that belongs to the group of nocardioform actinomycetes having the ability to survive within macrophages of the animal, comprising live bacteria of a nocardioform actinomycetes species, the live bacteria being attenuated by inactivation of a gene that encodes a protein involved in methylhexahydroindanedione propionate degradation, and a pharmaceutically acceptable carrier for these live bacteria.
(FR) L'invention porte sur une composition pharmaceutique destinée à protéger un animal contre un trouble causé par une infection par une bactérie qui appartient au groupe des actinomycètes nocardioformes ayant la capacité de survivre dans des macrophages de l'animal, comprenant des bactéries vivantes de l'espèce actinomycète nocardioforme, les bactéries vivantes étant atténuées par l'inactivation d'un gène codant pour une protéine impliquée dans la dégradation du propionate de méthylhexahydroindanedione, et un vecteur pharmaceutiquement acceptable pour ces bactéries vivantes.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2385836JP2012515147US20110274660CN102271693RU2011133824CA2749075
RU0002543663BRPI1006875NZ593588AU2010204269IN4877/CHENP/2011