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1. (WO2010079079) PDGF-Rβ BINDERS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/079079 International Application No.: PCT/EP2009/067447
Publication Date: 15.07.2010 International Filing Date: 17.12.2009
IPC:
A61K 49/14 (2006.01) ,A61K 51/08 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49
Preparations for testing in vivo
06
Nuclear magnetic resonance (NMR) contrast preparations; Magnetic resonance imaging (MRI) contrast preparations
08
characterised by the carrier
10
Organic compounds
14
Peptides, e.g. proteins
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51
Preparations containing radioactive substances for use in therapy or testing in vivo
02
characterised by the carrier
04
Organic compounds
08
Peptides, e.g. proteins
Applicants:
GENERAL ELECTRIC COMPANY [US/US]; 1 River Road Schenectady, New York 12345, US (AllExceptUS)
MARINO, Michael Ernest [US/US]; US (UsOnly)
SYUD, Faisal Ahmed [US/US]; US (UsOnly)
SCHAFFER, Paul [CA/CA]; CA (UsOnly)
LEE, Brian Duh-Lan [US/US]; US (UsOnly)
ZHANG, Rong [CN/US]; US (UsOnly)
LINDBORG, Malin [SE/SE]; SE (UsOnly)
GUNNERIUSSON, Elin [SE/SE]; SE (UsOnly)
LENDEL, Christofer [SE/SE]; SE (UsOnly)
Inventors:
MARINO, Michael Ernest; US
SYUD, Faisal Ahmed; US
SCHAFFER, Paul; CA
LEE, Brian Duh-Lan; US
ZHANG, Rong; US
LINDBORG, Malin; SE
GUNNERIUSSON, Elin; SE
LENDEL, Christofer; SE
Agent:
CANNING, Lewis Reuben; GE Healthcare Limited Pollards Wood Nightingales Lane Chalfont St Giles Buckinghamshire HP8 4SP, GB
Priority Data:
12/336,78017.12.2008US
Title (EN) PDGF-Rβ BINDERS
(FR) AGENTS SE LIANT AU PDGF-RΒ
Abstract:
(EN) Provided herein are PDGF-Rβ imaging agents that are polypeptides labeled with a signal generator (e.g., paramagnetic label, a radionuclide, or a fluorophore), wherein the imaging agents bind specifically to PDGFR-β. Also provided are in vivo imaging methods using the imaging agents.
(FR) Cette invention concerne des agents d'imagerie PDGF-Rβ qui sont des polypeptides marqués avec un générateur de signal (par exemple marqueur paramagnétique, isotope ou fluorophore), lesdits agents d'imagerie se liant spécifiquement au PDGF-Rβ. L'invention décrit également des procédés d'imagerie in vivo utilisant lesdits agents d'imagerie.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2381966JP2012512233CN102316903