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1. (WO2010079047) OCTREOTIDE DEPOT FORMULATION WITH CONSTANTLY HIGH EXPOSURE LEVELS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/079047 International Application No.: PCT/EP2009/067049
Publication Date: 15.07.2010 International Filing Date: 14.12.2009
IPC:
A61K 47/10 (2006.01) ,A61K 47/26 (2006.01) ,A61K 47/38 (2006.01) ,A61K 38/31 (2006.01) ,A61K 9/16 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
08
containing oxygen
10
Alcohols; Phenols; Salts thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
26
Carbohydrates
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
36
Polysaccharides; Derivatives thereof
38
Cellulose; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
22
Hormones
31
Somatostatins
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
16
Agglomerates; Granulates; Microbeadlets
Applicants:
NOVARTIS AG [CH/CH]; Lichtstrasse 35 CH-4056 Basel, CH (AllExceptUS)
AHLHEIM, Markus [DE/CH]; CH (UsOnly)
PETERSEN, Holger [DE/CH]; CH (UsOnly)
Inventors:
AHLHEIM, Markus; CH
PETERSEN, Holger; CH
Agent:
GRUBER, Markus; NOVARTIS PHARMA AG Patent Department CH-4002 Basel, CH
Priority Data:
08171712.615.12.2008EP
Title (EN) OCTREOTIDE DEPOT FORMULATION WITH CONSTANTLY HIGH EXPOSURE LEVELS
(FR) FORMULATION À EFFET RETARD D'OCTRÉOTIDE AVEC NIVEAUX D'EXPOSITION CONSTAMMENT ÉLEVÉS
Abstract:
(EN) The present invention relates to sustained release formulations comprising as active ingredient octreotide or a pharmaceutically-acceptable salt thereof and two different linear polylactide-co-glycolide polymers (PLGAs).
(FR) La présente invention porte sur des formulations à libération entretenue comprenant en tant qu'ingrédient actif de l'octréotide ou un sel pharmaceutiquement acceptable de celle-ci et deux polymères polylactide-co-glycolide linéaires différents (PLGA).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
DZDZP2011000440AR074603IL213034MXMX/a/2011/006335SG171255EP2376070
US20100151033US20100266704MA32964JP2012512147US20110262545CN102245210
RU2011128538CA2746968RU0002526822US20140363513MX2011006335CO6382109
CL2011001438KR1020110104042TN2011000261CN105031607BRPI0922607US20160089336
NZ592998AU2009336718ES2602614US20170143791ID051.4329MYPI 2011002392
IN3725/DELNP/2011US20180036230PT2376070