Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2010078966) FUSION PROTEINS FORMING TRIMERS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/078966 International Application No.: PCT/EP2009/050233
Publication Date: 15.07.2010 International Filing Date: 09.01.2009
IPC:
C07K 14/525 (2006.01) ,C12N 15/62 (2006.01) ,C07K 14/47 (2006.01) ,C07K 14/705 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
52
Cytokines; Lymphokines; Interferons
525
Tumour necrosis factor (TNF)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
62
DNA sequences coding for fusion proteins
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
705
Receptors; Cell surface antigens; Cell surface determinants
Applicants:
apogenix GmbH; Im Neuenheimer Feld 584 69120 Heidelberg, DE (AllExceptUS)
HILL, Oliver [DE/DE]; DE (UsOnly)
BRANSCHAEDEL, Marcus [DE/DE]; DE (UsOnly)
GIEFFERS, Christian [DE/DE]; DE (UsOnly)
THIEMANN, Meinolf [DE/DE]; DE (UsOnly)
Inventors:
HILL, Oliver; DE
BRANSCHAEDEL, Marcus; DE
GIEFFERS, Christian; DE
THIEMANN, Meinolf; DE
Agent:
MARTIN, Peter; mtm laboratories AG Im Neuenheimer Feld 583 69120 Heidleberg, DE
Priority Data:
Title (EN) FUSION PROTEINS FORMING TRIMERS
(FR) PROTÉINES DE FUSION FORMANT DES TRIMÈRES
Abstract:
(EN) The present invention refers to fusion proteins comprising a neck region and carbohydrate recognition domain of a collectin trimerization domain, a linker element and an effector polypeptide. Further the invention refers to a nucleic acid encoding the said fusion protein. The fusion proteins, the nucleic acid, and the cell are suitable as pharmaceutical composition or for therapeutic, diagnostic and/or research applications as described herein.
(FR) La présente invention concerne des protéines de fusion comprenant une région centrale et un domaine de reconnaissance des glucides d'un domaine de trimérisation des collectines, un élément de liaison et un polypeptide effecteur. L'invention concerne en outre un acide nucléique codant pour ladite protéine de fusion. Les protéines de fusion, l'acide nucléique et la cellule sont appropriés en tant que composition pharmaceutique ou pour des applications thérapeutiques, diagnostiques et/ou de recherche telles que décrites ici.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2382236JP2012514616US20120041181EP2829550ES2593049