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1. (WO2010078730) PREPARATION OF GINSENOSIDE-RD PROPYLENE GLYCOL AQUEOUS SOLUTION AND NEW USE THEREOF IN ANTI-INFLAMMATION, IMMUNOSUPPRESSION AND ANTI ORGAN-GRAFT REJECTION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/078730 International Application No.: PCT/CN2009/070419
Publication Date: 15.07.2010 International Filing Date: 13.02.2009
IPC:
A61K 31/704 (2006.01) ,A61P 29/00 (2006.01) ,A61P 37/06 (2006.01) ,A61P 19/02 (2006.01) ,A61P 19/08 (2006.01) ,A61P 9/00 (2006.01) ,A61P 43/00 (2006.01) ,A61K 36/258 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7028
Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
7034
attached to a carbocyclic compound, e.g. phloridzin
704
attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29
Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
02
Immunomodulators
06
Immunosuppressants, e.g. drugs for graft rejection
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19
Drugs for skeletal disorders
02
for joint disorders, e.g. arthritis, arthrosis
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19
Drugs for skeletal disorders
08
for bone diseases, e.g. rachitism, Paget's disease
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9
Drugs for disorders of the cardiovascular system
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43
Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18
Magnoliophyta (angiosperms)
185
Magnoliopsida (dicotyledons)
25
Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
258
Panax (ginseng)
Applicants:
广东泰禾医药科技有限公司 GUANGDONG TAIHE MEDICINE SCIENCE & TECHNOLOGY CO., LTD [CN/CN]; 中国广东省广州市天河科技园建中路6号2楼, Guangdong 510665 Floor 2, No.6, Jianzhong Rd, Tianhe Science And Technology Park Guangzhou, Guangdong 510665, CN (AllExceptUS)
范富林 FAN, Fulin [CN/CN]; CN (UsOnly)
徐晓非 WANG, Eric [US/US]; US (UsOnly)
Inventors:
范富林 FAN, Fulin; CN
徐晓非 WANG, Eric; US
Agent:
上海专利商标事务所有限公司 SHANGHAI PATENT & TRADEMARK LAW OFFICE, LLC; 中国上海市徐汇区桂平路435号, Shanghai 200233 435 Guiping Road, Xuhui Shanghai 200233, CN
Priority Data:
200810208119.229.12.2008CN
Title (EN) PREPARATION OF GINSENOSIDE-RD PROPYLENE GLYCOL AQUEOUS SOLUTION AND NEW USE THEREOF IN ANTI-INFLAMMATION, IMMUNOSUPPRESSION AND ANTI ORGAN-GRAFT REJECTION
(FR) PRÉPARATION D'UNE SOLUTION AQUEUSE DE GINSÉNOSIDE-RD PROPYLÈNEGLYCOL ET NOUVELLE UTILISATION DE CETTE DERNIÈRE COMME ANTI-INFLAMMATOIRE, IMMUNOSUPPRESSEUR ET ANTIREJET DE GREFFE D'ORGANE
(ZH) 人参皂苷-Rd丙二醇水溶液制备及其抗炎、免疫抑制与抗器官移植排斥的新用途
Abstract:
(EN) The present invention provides preparation of ginsenoside-Rd propylene glycol aqueous solution and new use thereof in anti-inflammation, immunosuppression and anti organ-graft refection. The present invention provides a ginsenoside-Rd solution and preparation method thereof, said solution is prepared by adding ginsenoside-Rd to propylene glycol aqueous solution comprising 50-100%(v) propylene glycol, the content of ginsenoside-Rd is 1-100mg/ml solution, wherein the standard of the volume percentage is the bulk volume of propylene glycol aqueous solution. Furthermore, the present invention provides a medical composition of solution of the present invention and preparation method thereof, and the use of ginsenoside-Rd or ginsenoside-Rd solution of the present invention in manufacture of medicaments for anti-inflammation, immuneosuppression and/or anti organ-graft rejection.
(FR) L'invention concerne la préparation d'une solution aqueuse de ginsénoside-Rd propylèneglycol et une nouvelle utilisation de cette dernière comme anti-inflammatoire, immunosuppresseur et antirejet de greffe d'organe. L'invention concerne une solution de ginsénoside-Rd et son procédé de préparation, ladite solution étant préparée par ajout de ginsénoside-Rd à une solution aqueuse de propylèneglycol comprenant 50-100% en volume(v) de propylèneglycol, la teneur de ginsénoside-Rd étant de 1-100mg/ml de la solution, le pourcentage volumétrique normal étant le volume apparent de la solution aqueuse de propylèneglycol. L'invention concerne également une composition médicale à base de la solution de l'invention et son procédé de préparation, et l'utilisation de ginsénoside-Rd ou d'une solution de ginsénoside-Rd pour préparer des médicaments anti-inflammatoires, immunosuppresseurs et antirejet de greffe d'organe.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)