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1. (WO2010078543) TABLET CONTAINING CETIRIZINE PSEUDOEPHEDRINE, AND NAPROXEN CONTAINING A BARRIER LAYER
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/078543 International Application No.: PCT/US2010/020023
Publication Date: 08.07.2010 International Filing Date: 04.01.2010
IPC:
A61K 9/20 (2006.01) ,A61K 31/137 (2006.01) ,A61K 31/192 (2006.01) ,A61K 31/495 (2006.01) ,A61P 37/08 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
13
Amines, e.g. amantadine
135
having aromatic rings, e.g. methadone
137
Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
192
having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
08
Antiallergic agents
Applicants:
MCNEIL-PPC, INC. [US/US]; 199 Grandview Road Skillman, NJ 08558, US (AllExceptUS)
KAMATH, Satish [US/US]; US (UsOnly)
SHAH, Indukumar, G. [US/US]; US (UsOnly)
NICHOLS, Michael [US/US]; US (UsOnly)
PATEL, Dinesh [US/US]; US (UsOnly)
Inventors:
KAMATH, Satish; US
SHAH, Indukumar, G.; US
NICHOLS, Michael; US
PATEL, Dinesh; US
Agent:
JOHNSON, Philip, S.; Johnson & Johnson One Johnson & Johnson Plaza New Brunswick, NJ 08933, US
Priority Data:
61/142,43105.01.2009US
Title (EN) TABLET CONTAINING CETIRIZINE PSEUDOEPHEDRINE, AND NAPROXEN CONTAINING A BARRIER LAYER
(FR) COMPRIMÉ CONTENANT DE LA PSEUDOÉPHÉDRINE DE CÉTIRIZINE, ET NAPROXÈNE CONTENANT UNE COUCHE BARRIÈRE
Abstract:
(EN) In one aspect, the present invention features a tablet including: (i) a first drug layer including naproxen; (ii) a second drug layer including a decongestant (e.g., pseudoephedrine) wherein said second drug layer is a sustained release layer adapted to deliver a therapeutically effective amount of pseudoephedrine for a period of at least twelve hours; and (iii) a barrier layer that does not include naproxen, wherein the barrier layer is in contact with the first drug layer; and (iv) a third drug layer including cetirizine, wherein the third drug layer is in contact with the barrier layer and is not in contact with the first drug layer.
(FR) Selon un aspect, la présente invention porte sur un comprimé comprenant : (i) une première couche de médicament comprenant du naproxène ; (ii) une seconde couche de médicament comprenant un décongestionnant (par exemple de la pseudoéphédrine), ladite seconde couche de médicament étant une couche à libération entretenue apte à administrer une quantité thérapeutiquement efficace de pseudoéphédrine pendant une période de temps d'au moins 12 heures ; et (iii) une couche barrière ne comprenant pas de naproxène, la couche barrière étant en contact avec la première couche de médicament ; et (iv) une troisième couche de médicament comprenant de la cétirizine, la troisième couche de médicament étant en contact avec la couche barrière et n'étant pas en contact avec la première couche de médicament.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
CA2748728