Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2010078043) ADHESIVE CARTILAGE IMPLANT
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/078043 International Application No.: PCT/US2009/068494
Publication Date: 08.07.2010 International Filing Date: 17.12.2009
IPC:
A61F 2/08 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
2
Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
02
Prostheses implantable into the body
08
Muscles; Tendons; Ligaments
Applicants:
HOWMEDICA OSTEONICS CORP. [US/US]; 325 Corporate Drive Mahwah, NJ 07430, US (AllExceptUS)
SONG, Lin [CN/US]; US (UsOnly)
Inventors:
SONG, Lin; US
Agent:
TOMKINS, Brian, R.; Lerner, David, Littenberg, Krumholz & Mentlik, LLP 600 South Avenue West Westfield, NJ 07090, US
Priority Data:
12/319,12931.12.2008US
Title (EN) ADHESIVE CARTILAGE IMPLANT
(FR) IMPLANT DE CARTILAGE ADHÉSIF
Abstract:
(EN) A method of producing a cartilage implant which may include coating a substrate with a thermo-sensitive polymer, seeding the polymer with a cell suspension comprising cells that may differentiate into chrondocyte-like cells, wherein the seeding may be conducted at a first temperature, culturing the cell suspension at an increased temperature, whereby cells in the suspension may adhere to the polymer and differentiate into chrondrocyte-like cells, which may form a cartilagenous implant, and decreasing the temperature of the polymer which may allow detachment of the implant from the polymer. The present invention may also include an implant based on this method. The invention may further include a cartilage implant for use in a patient in need thereof, which may include a random three-dimensional configuration of differentiated cells, which may have a natural adhesion surface on at least a portion of the outer surface of the three-dimensional configuration.
(FR) La présente invention concerne un procédé de production d'un implant de cartilage qui peut comprendre le revêtement d'un substrat avec un polymère thermosensible, l'inoculation du polymère avec une suspension de cellules comprenant des cellules qui peuvent se différencier en cellules de type chrondocyte, où l'inoculation peut être effectuée à une première température, la culture de la suspension de cellules à une température augmentée, de sorte que les cellules dans la suspension puissent adhérer au polymère et se différencier en cellules de type chrondocyte, qui peuvent former un implant cartilagineux, et la diminution de la température du polymère qui peut permettre le détachement de l'implant du polymère. La présente invention peut comprendre en outre un implant basé sur ce procédé. L'invention peut comprendre en outre un implant de cartilage pour utilisation chez un patient nécessitant celui-ci, qui peut comprendre une configuration tridimensionnelle aléatoire de cellules différenciées, qui peut comporter une surface d'adhésion naturelle sur au moins une partie de la surface externe de la configuration tridimensionnelle.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)