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1. (WO2010077858) GENES ENCODING NEMATODE TOXINS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/077858 International Application No.: PCT/US2009/068037
Publication Date: 08.07.2010 International Filing Date: 15.12.2009
IPC:
C12N 9/02 (2006.01) ,C12N 15/82 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
02
Oxidoreductases (1.), e.g. luciferase
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79
Vectors or expression systems specially adapted for eukaryotic hosts
82
for plant cells
Applicants:
ATHENIX CORPORATION [US/US]; P.o. Box 110347 Research Triangle Park, NC 27709, US (AllExceptUS)
PETERS, Cheryl, L. [US/US]; US (UsOnly)
VANDE BERG, Brian [US/US]; US (UsOnly)
CARR, Brian [US/US]; US (UsOnly)
DAUM, Julia, T. [US/US]; US (UsOnly)
BEILINSON, Vadim [EE/US]; US (UsOnly)
VOLRATH, Sandra [US/US]; US (UsOnly)
POUTRE, Candace [US/US]; US (UsOnly)
SAMPSON, Kimberly, S. [US/US]; US (UsOnly)
KAHN, Theodore [US/US]; US (UsOnly)
Inventors:
PETERS, Cheryl, L.; US
VANDE BERG, Brian; US
CARR, Brian; US
DAUM, Julia, T.; US
BEILINSON, Vadim; US
VOLRATH, Sandra; US
POUTRE, Candace; US
SAMPSON, Kimberly, S.; US
KAHN, Theodore; US
Agent:
MCBEE, Susan, E., Shaw; Baker Donelson Bearman, Caldwell & Berkowitz, PC 555 11th Street, 6th Floor Washington, DC 20004, US
Priority Data:
61/122,67415.12.2008US
61/224,81110.07.2009US
Title (EN) GENES ENCODING NEMATODE TOXINS
(FR) GÈNE CODANT DES TOXINES CONTRE LES NÉMATODES
Abstract:
(EN) Compositions and methods for conferring nematicidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions including a coding sequence for nematicidal polypeptides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also include transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated nematicidal nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated nucleic acid molecules including nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:5, 4, 8, 9, 13, 14, 47, 48, or 49, the nucleotide sequence set forth in SEQ ID NO:3, 1, 2, 6, 7, 10, 11, 12, 15, 45, or 46, as well as variants and fragments thereof.
(FR) La présente invention concerne des compositions et des méthodes conférant une activité nématicide à des bactéries, des végétaux, des tissus, des graines et des cellules végétales. La présente invention concerne des compositions incluant une séquence codant des polypeptides nématicides. Les séquences codantes peuvent être employées dans des constructions d'ADN ou des cassettes d'expression pour la transformation et l'expression chez des végétaux et des bactéries. Les compositions incluent également des bactéries, végétaux, tissus, graines et cellules végétales transformés. En particulier, la présente invention concerne des molécules d'acide nucléique nématicides isolées. De plus, la présente invention englobe les séquences d'acides aminés correspondant aux polynucléotides. En particulier, la présente invention concerne des molécules d'acide nucléique isolées incluant des séquences nucléotidiques codant la séquence d'acides aminés présentées dans les SEQ ID NO:5, 4, 8, 9, 13, 14, 47, 48 ou 49, les séquences nucléotidiques présentées dans les SEQ ID NO:3, 1, 2, 6, 7, 10, 11, 12, 15, 45 ou 46, ainsi que leurs variantes et leurs fragments.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2366025CN102369280CA2746766EA201170685ID2012/01528IN4450/DELNP/2011