Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2010077839) SUBSTITUTED OXINDOL CB2 AGONISTS FOR PAIN TREATMENT
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/077839 International Application No.: PCT/US2009/067967
Publication Date: 08.07.2010 International Filing Date: 15.12.2009
IPC:
C07D 209/34 (2006.01) ,C07D 209/38 (2006.01) ,C07D 491/10 (2006.01) ,A61K 31/404 (2006.01) ,A61P 25/04 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
209
Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
02
condensed with one carbocyclic ring
04
Indoles; Hydrogenated indoles
30
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
32
Oxygen atoms
34
in position 2
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
209
Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
02
condensed with one carbocyclic ring
04
Indoles; Hydrogenated indoles
30
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
32
Oxygen atoms
38
in positions 2 and 3, e.g. isatin
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
491
Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/-C07D459/290
02
in which the condensed system contains two hetero rings
10
Spiro-condensed systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
40
having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
403
condensed with carbocyclic rings, e.g. carbazole
404
Indoles, e.g. pindolol
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
04
Centrally acting analgesics, e.g. opioids
Applicants:
WYETH LLC (FORMERLY KNOWN AS WYETH) [US/US]; Five Giralda Farms Madison, New Jersey 07940, US (AllExceptUS)
DOLLINGS, Paul, Jeffrey [US/US]; US (UsOnly)
DONNELL, Andrew, Forrest [US/US]; US (UsOnly)
GILBERT, Adam, Matthew [US/US]; US (UsOnly)
ZHANG, Minsheng [US/US]; US (UsOnly)
HARRISON, Boyd, Lynn [US/US]; US (UsOnly)
STANTON III, Charles, John [US/US]; US (UsOnly)
O'NEIL, Steven, Victor [US/US]; US (UsOnly)
HAVRAN, Lisa, Marie [US/US]; US (UsOnly)
CHONG, Dan, Chaekoo [US/US]; US (UsOnly)
Inventors:
DOLLINGS, Paul, Jeffrey; US
DONNELL, Andrew, Forrest; US
GILBERT, Adam, Matthew; US
ZHANG, Minsheng; US
HARRISON, Boyd, Lynn; US
STANTON III, Charles, John; US
O'NEIL, Steven, Victor; US
HAVRAN, Lisa, Marie; US
CHONG, Dan, Chaekoo; US
Agent:
JOHNSON, Stephen, E.; Pfizer (formerly known as Wyeth) Patent Law Department Five Giralda Farms Madison, New Jersey 07940, US
Priority Data:
61/122,55715.12.2008US
Title (EN) SUBSTITUTED OXINDOL CB2 AGONISTS FOR PAIN TREATMENT
(FR) AGONISTES DE CB2 DE TYPE OXINDOLE SUBSTITUÉ POUR LE TRAITEMENT DE LA DOULEUR
Abstract:
(EN) Provided are 3-substituted oxindole derivatives which are agonists of the CB2 receptor, pharmaceutical compositions containing the same, and methods of treatment related to CB2-mediated disorders (e.g., pain, cancer etc.) using the 3-substituted oxindole derivatives and compositions described herein.
(FR) L'invention porte sur des dérivés oxindoles substitués en position 3 qui sont des agonistes du récepteur CB2, sur des compositions pharmaceutiques les contenant et sur des procédés de traitement concernant des troubles à médiation par CB2 (par exemple la douleur, le cancer, etc.) à l'aide des dérivés oxindoles substitués en position 3 et des compositions décrites par les présentes.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)