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1. (WO2010077794) RADIOACTIVE GOLD NANOPARTICLES AND METHODS OF MAKING AND USING THEM
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/077794 International Application No.: PCT/US2009/067808
Publication Date: 08.07.2010 International Filing Date: 14.12.2009
IPC:
B22F 9/02 (2006.01) ,B22F 9/24 (2006.01)
B PERFORMING OPERATIONS; TRANSPORTING
22
CASTING; POWDER METALLURGY
F
WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
9
Making metallic powder or suspensions thereof; Apparatus or devices specially adapted therefor
02
using physical processes
B PERFORMING OPERATIONS; TRANSPORTING
22
CASTING; POWDER METALLURGY
F
WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
9
Making metallic powder or suspensions thereof; Apparatus or devices specially adapted therefor
16
using chemical processes
18
with reduction of metal compounds
24
starting from liquid metal compounds, e.g. solutions
Applicants:
NATIONAL HEALTH RESEARCH INSTITUTES; No. 35, Keyan Road, Zhunan Town, Miaoli County 350, Taiwan, R.O.C., TW (AllExceptUS)
NATIONAL TSING HUA UNIVERSITY; No. 101, Section 2, Kuang-Fu Road, Hsinchu 300, Taiwan, R.O.C., TW (AllExceptUS)
HO, Ing-Kang [US/US]; US (CN)
CHEN, Jen-Kun; TW (UsOnly)
PEIR, Jinn-Jer; TW (UsOnly)
WANG, Mei-Ya; TW (UsOnly)
LIU, Chih-Hui; TW (UsOnly)
CHOU, Fong-In; TW (UsOnly)
YANG, Chung-Shi; TW (UsOnly)
YANG, Mo-Hsiung; TW (UsOnly)
SHIH, Mei-Hui; TW (UsOnly)
Inventors:
CHEN, Jen-Kun; TW
PEIR, Jinn-Jer; TW
WANG, Mei-Ya; TW
LIU, Chih-Hui; TW
CHOU, Fong-In; TW
YANG, Chung-Shi; TW
YANG, Mo-Hsiung; TW
SHIH, Mei-Hui; TW
Agent:
SAUNDERS, Hsiu-Ming; IPC Intellectual Property Connections, Inc. 299 Old County Road, Suite 28 San Carlos, CA 94070, US
Priority Data:
61/138,51117.12.2008US
Title (EN) RADIOACTIVE GOLD NANOPARTICLES AND METHODS OF MAKING AND USING THEM
(FR) NANOPARTICULES D'OR RADIOACTIVES ET PROCÉDÉS DE PRÉPARATION ET D'UTILISATION DE CELLES-CI
Abstract:
(EN) Methods of preparing a composition comprising non-ionic, radioactive gold nanoparticles (R-GNPs) are disclosed. The method comprises: a) providing a solution comprising gold (Au-197) ions; and b) exposing the solution to neutron irradiation to generate a composition comprising non-ionic R-GNPs. Alternatively, the method comprises: a) providing a solution that comprises a composition comprising gold (Au-197) nanoparticles (GNPs); and b) exposing the GNP solution to neutron irradiation to generate a composition comprising non-ionic R-GNPs. Compositions that comprises non-ionic R-GNPs encapsulated within and/or anchored to MSNs, and methods of making the same are also disclosed.
(FR) L'invention porte sur des procédés de préparation d'une composition qui comporte des nanoparticules d'or radioactives non ioniques (R-GNP). Le procédé comporte : a) l'utilisation d'une solution comportant des ions or (Au-197), et b) l'exposition de la solution à une irradiation par des neutrons pour générer une composition comportant des nanoparticules d'or radioactives non ioniques. En variante, le procédé comporte : a) l'utilisation d'une solution qui comporte une composition comportant des nanoparticules d'or (Au-197) (GNP), et b) l'exposition de la solution de nanoparticules d'or à une irradiation par des neutrons pour générer une composition comportant des nanoparticules d'or radioactives non ioniques. L'invention porte également sur des compositions qui comportent des nanoparticules d'or radioactives non ioniques encapsulées à l'intérieur de nanoparticules de silice mésoporeuse (MSN) et/ou ancrées sur celles-ci, et sur des procédés de préparation de celles-ci.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2373450JP2012512332CA2743315AU2009333387