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1. (WO2010077752) IMIDAZOLINONE DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/077752 International Application No.: PCT/US2009/067412
Publication Date: 08.07.2010 International Filing Date: 10.12.2009
IPC:
A01N 43/50 (2006.01)
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
N
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
43
Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
48
having rings with two nitrogen atoms as the only ring hetero atoms
50
1,3-Diazoles; Hydrogenated 1,3-diazoles
Applicants:
MERCK SHARP & DOHME CORP. [US/US]; 126 East Lincoln Avenue Rahway, New Jersey 07065-0907, US (AllExceptUS)
SELNICK, Harold G. [US/US]; US (UsOnly)
WOOD, Michael R. [US/US]; US (UsOnly)
MCWHERTER, Melody [US/US]; US (UsOnly)
HILLS, Ivory D. [US/US]; US (UsOnly)
STUMP, Craig A. [US/US]; US (UsOnly)
Inventors:
SELNICK, Harold G.; US
WOOD, Michael R.; US
MCWHERTER, Melody; US
HILLS, Ivory D.; US
STUMP, Craig A.; US
Common
Representative:
MERCK SHARP & DOHME CORP.; 126 East Lincoln Avenue Rahway, New Jersey 07065-0907, US
Priority Data:
61/138,16117.12.2008US
Title (EN) IMIDAZOLINONE DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS
(FR) DÉRIVÉS D'IMIDAZOLINONE EN TANT QU'ANTAGONISTES DE RÉCEPTEURS CGRP
Abstract:
(EN) The present invention is directed to imidazolinone derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
(FR) La présente invention concerne des dérivés d'imidazolinone qui sont des antagonistes des récepteurs CGRP et peuvent être employés dans le traitement prophylactique ou thérapeutique de pathologies impliquant CGRP, par exemple la migraine. La présente invention concerne également des compositions pharmaceutiques comprenant lesdits composés, ainsi que l'emploi desdits composés et compositions dans le traitement prophylactique ou thérapeutique de pathologies impliquant les récepteurs CGRP.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2378877JP2012512248US20110306626CA2746671AU2009333427