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1. (WO2010077712) BOVINE RESPIRATORY SYNCYTIAL VIRUS VIRUS-LIKE PARTICLE (VLPS)
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/077712 International Application No.: PCT/US2009/067257
Publication Date: 08.07.2010 International Filing Date: 09.12.2009
IPC:
A61K 39/155 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
12
Viral antigens
155
Paramyxoviridae, e.g. parainfluenza virus
Applicants:
NOVAVAX, INC. [US/US]; 9920 Belward Campus Drive Rockville, Maryland 20850, US (AllExceptUS)
MASSARE, Michael J. [US/US]; US (UsOnly)
SMITH, Gale E. [US/US]; US (UsOnly)
Inventors:
MASSARE, Michael J.; US
SMITH, Gale E.; US
Agent:
WICKMAN, Paul A.; Cooley LLP 777 6th Street, NW Suite 1100 Washington, DC 20001, US
Priority Data:
61/121,12609.12.2008US
Title (EN) BOVINE RESPIRATORY SYNCYTIAL VIRUS VIRUS-LIKE PARTICLE (VLPS)
(FR) PARTICULE DE TYPE VIRAL DU VIRUS SYNCYTIAL RESPIRATOIRE BOVIN (VLPS)
Abstract:
(EN) Disclosed are virus like particles (VLPs) comprising bovine RSV (BRSV) matrix proteins. Further disclosed are vector constructs comprising bovine RSV (BRSV) matrix proteins, cells comprising the constructs, formulations and vaccines comprising VLPs. Also incuded are methods of making and administrating VLPs to vertebrates, including methods of inducing immunity to infections, including RSV.
(FR) La présente invention porte sur des particules de type viral (VLP) comprenant des protéines matricielles de RSV bovin (BRSV). L'invention comprend des produits de construction de vecteur contenant des protéines matricielles de RSV bovin (BRSV), des cellules contenant les produits de construction, des formulations et des vaccins contenant les VLP de l'invention. L'invention porte également sur des procédés de fabrication et des méthodes d'administration des VLP à des vertébrés, comprenant des méthodes d'induction d'une immunité vis-à-vis des infections, dont le RSV.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)