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1. (WO2010077364) STROKE-GENERATED ANGIOGENESIS ENHANCERS AND USES THEREOF
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2010/077364 International Application No.: PCT/US2009/006758
Publication Date: 08.07.2010 International Filing Date: 31.12.2009
IPC:
A61K 38/17 (2006.01) ,A61P 9/10 (2006.01) ,A61P 25/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9
Drugs for disorders of the cardiovascular system
10
for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
Applicants:
THE TEXAS A & M UNIVERSITY SYSTEM [US/US]; 3369 Tamu College Station, TX 77843-3369, US (AllExceptUS)
Inventors:
BIX, Gregory, J.; US
Agent:
ADLER, Benjamin, Aaron, Ph. D., J. D.; Adler & Associates 8011 Candle Lane Houston, TX 77071, US
Priority Data:
61/204,06431.12.2008US
Title (EN) STROKE-GENERATED ANGIOGENESIS ENHANCERS AND USES THEREOF
(FR) STIMULATEURS D'ANGIOGENÈSE GÉNÉRÉS PAR UN ACCIDENT VASCULAIRE CÉRÉBRAL ET LEURS UTILISATIONS
Abstract:
(EN) The present invention is drawn to methods of stimulating or enhancing angiogenesis in a patient comprising, administering to said patient a therapeutically effective amount of an endorepellin protein, wherein said endorepellin protein has an amino acid sequence of domain V of perlecan or fragments or derivatives, analogs thereof; and stimulating or enhancing generation of blood vessels. The present invention is drawn to compositions for enhancing angiogenesis.
(FR) Cette invention concerne des procédés de stimulation ou d'accélération de l'angiogenèse chez un patient, lesdits procédés comprenant les étapes consistant à administrer audit patient une quantité thérapeutiquement efficace d'endorepelline, ladite endorepelline comportant une séquence d'acides aminés du domaine V du perlecan ou des fragments, des dérivés ou des analogues de celui-ci; et à stimuler ou à accélérer la génération de vaisseaux sanguins. L'invention concerne également des compositions accélérant l'angiogenèse.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2373328JP2012514036CN102355905RU2011131772CA2748811CN104208659
MX2011007108ES2524366KR1020110127131BRPI0924061AU2009333815